ReviewFrontiers in cellular neuroscience2023
Consequences of spinal cord injury on the sympathetic nervous system.
Review in Frontiers in cellular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spinal cord stimulation to manage autonomic dysfunction after spinal cord injury: a systematic review.Frontiers in human neuroscience · 2026Pooled it
- Effects of 12 weeks of upper-body rowing exercise on autonomic cardiovascular control and vascular structure in spinal cord-injured humans.Experimental physiology · 2026Trial
- Vitamin D Supplementation Adjunct to Home-Based Electrical Stimulation Exercise Program Versus Passive Movement Training in Chronic SCI: Individual Results From Trial Under Accrual.Topics in spinal cord injury rehabilitation · 2025Trial
- Exercise and Autonomic Cardiovascular Function-Insights From Spinal Cord-Injured Humans: A Narrative Review.Acta physiologica (Oxford, England) · 2026Review
- Restoration of gamma-aminobutyric acid homeostasis: A novel approach to alleviating central nervous system injury-associated immunodepression syndrome.Neural regeneration research · 2026Article
- Blood pressure variability in daily life: comparing individuals with cervical and upper-thoracic spinal cord injury to non-injured controls.Journal of human hypertension · 2026Article
- Frequency-Domain Analysis Links Autonomic Disruption to Renal Autoregulatory Failure after Spinal Cord Injury.bioRxiv : the preprint server for biology · 2026Article
- Swimming exercise training (SET) and MitoQ supplementation can mitigate the atrophy and inflammation process in skeletal muscles of male Wistar rats with spinal cord injury (SCI): NF-κB/MuRF-1/proteasome pathway.Biochemistry and biophysics reports · 2026Article
- Evaluation and management of autonomic functions in patients with spinal cord injury: A scoping review.The journal of spinal cord medicine · 2026Article
- Early Versus Late Tracheostomy in Traumatic Spinal Injury: A Narrative Review.Neurology international · 2026Review
- Article
- Focal Estrogen Therapy in Male Rats Promotes Neuronal Survival and Reduces Denervation Atrophy After Spinal Cord Injury via Modulation of β-Catenin and NF-κB.Neurochemical research · 2026Article
- Rewiring the Lung-CNS Axis After Spinal Cord Injury.Journal of inflammation research · 2026Review
- Peripheral Sympathetic Sprouting Drives Neuropathic Pain via Spinal Microglial P2Y12 Activation in a Rat Spinal Nerve Ligation Model.Journal of pain research · 2026Article
- Machine learning-driven prediction of in-hospital cardiac arrest among critically ill patients with traumatic spinal cord injury: a multicenter cohort study.Frontiers in cardiovascular medicine · 2026Article
- Autonomic dysreflexia: the concealed killer behind recurrent cerebral hemorrhage in spinal cord injury-a case report with management insights.Frontiers in neuroscience · 2026Article
- The Effect of Cefazolin on the Gut Microbiome of Female Rats After Spinal Cord Injury.Microorganisms · 2025Article
- Role of voltage-gated CaJournal of neurophysiology · 2025Article
- Chronic Pain Modulates Empathic Responses in People with Spinal Cord Injury.Journal of clinical medicine · 2025Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Spinal cord injury (SCI) damages multiple structures at the lesion site, including ascending, descending, and propriospinal axons; interrupting the conduction of information up and down the spinal cord. Additionally, axons associated with the autonomic nervous system that control involuntary physiological functions course through the spinal cord. Moreover, sympathetic, and parasympathetic preganglionic neurons reside in the spinal cord. Thus, depending on the level of an SCI, autonomic function can be greatly impacted by the trauma resulting in dysfunction of various organs. For example, SCI can lead to dysregulation of a variety of organs, such as the pineal gland, the heart and vasculature, lungs, spleen, kidneys, and bladder. Indeed, it is becoming more apparent that many disorders that negatively affect quality-of-life for SCI individuals have a basis in dysregulation of the sympathetic nervous system. Here, we will review how SCI impacts the sympathetic nervous system and how that negatively impacts target organs that receive sympathetic innervation. A deeper understanding of this may offer potential therapeutic insight into how to improve health and quality-of-life for those living with SCI.
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Registered trials
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