Evidence map›Paper›PMID 36925705›Full record

ArticleBioengineering & translational medicine2023

Electrostatic potential difference between tumor and paratumor regulates cancer stem cell behavior and prognose tumor spread.

Haoran Zhao, Weijie Zhang, Xiaowei Tang, Edgar A Galan, Yinheng Zhu, Gan Sang, Davit Khutsishvili, Honghui Zheng, Shaohua Ma

Open access · goldFull text read
In one paragraph

Article in Bioengineering & translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Haoran ZhaoTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.
Weijie ZhangDepartment of Oncology The First Affiliated Hospital, Zhengzhou University Zhengzhou China.
Xiaowei TangTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.
Edgar A GalanTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.ORCID https://orcid.org/0000-0002-2719-8470
Yinheng ZhuTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.
Gan SangTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.
Davit KhutsishviliTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.
Honghui ZhengTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.
Shaohua MaTsinghua Shenzhen International Graduate School (SIGS) Tsinghua University Shenzhen China.ORCID https://orcid.org/0000-0002-4995-2032
Tsinghua–Berkeley Shenzhen Institute · CNFirst Affiliated Hospital of Zhengzhou University · CNShenzhen Bay Laboratory · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor spread is responsible for most deaths related to cancer. Increasing the accuracy of cancer prognosis is critical to reducing the high mortality rates in cancer patients. Here, we report that the electrostatic potential difference (EPD) between tumor and its paratumor tissue is a prognostic marker for tumor spread. This finding is concluded from the patient-specific EPD values and clinical observation. The electrostatic potential values were measured on tissue cryosections from 51 patients using Kelvin probe force microscopy (KPFM). A total of ~44% (15/34) patients of V

Indexed as

cancer prognosiscancer stem cellselectrostatic potentialparatumortumortumor spread

Identifiers

PMID36925705
PMCPMC10013821
OpenAlexW4296831566

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read33
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.