Evidence map›Paper›PMID 36925700›Full record

ArticleBioengineering & translational medicine2023

Platelet membrane camouflaged AIEgen-mediated photodynamic therapy improves the effectiveness of anti-PD-L1 immunotherapy in large-burden tumors.

Jun Dai, Meng Wu, Yating Xu, Hongming Yao, Xiaoding Lou, Yuning Hong, Jian Zhou, Fan Xia, Shixuan Wang

Open access · goldFull text read
In one paragraph

Article in Bioengineering & translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Tumor-Targeted Delivery Therapy Based on PLGA Nanoparticles.Journal of functional biomaterials · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jun DaiDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Meng WuDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Yating XuCollege of Material, Chemistry and Chemical Engineering Hangzhou Normal University Hangzhou China.
Hongming YaoCollege of Material, Chemistry and Chemical Engineering Hangzhou Normal University Hangzhou China.
Xiaoding LouState Key Laboratory of Biogeology and Environmental Geology, Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry China University of Geosciences Wuhan China.
Yuning HongDepartment of Biochemistry and Chemistry, La Trobe Institute for Molecular Science La Trobe University Melbourne Victoria Australia.
Jian ZhouCollege of Material, Chemistry and Chemical Engineering Hangzhou Normal University Hangzhou China.
Fan XiaState Key Laboratory of Biogeology and Environmental Geology, Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry China University of Geosciences Wuhan China.
Shixuan WangDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.ORCID https://orcid.org/0000-0002-8610-952X
Hangzhou Normal University · CNTongji Hospital · CNChina University of Geosciences · CNLa Trobe University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although immunotherapy has achieved recent clinical success in antitumor therapy, it is less effective for solid tumors with large burdens. To overcome this challenge, herein, we report a new strategy based on platelet membrane-camouflaged aggregation-induced emission (AIE) luminogen (Plt-M@P) combined with the anti-programmed death ligand 1 (anti-PD-L1) for tumoral photodynamic-immunotherapy. Plt-M@P is prepared by using poly lactic-co-glycolic acid (PLGA)/PF3-PPh

Indexed as

aggregation‐induced emissionimmunotherapylarge‐burden tumorsPD‐L1photodynamic therapyplatelet membranes

Identifiers

PMID36925700
PMCPMC10013814
OpenAlexW4302307110

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read97
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.