Evidence map›Paper›PMID 36925669›Full record

ArticleFrontiers in pediatrics2023

Chemotherapy-induced cavitating Wilms' tumor pulmonary metastasis: Active disease or scarring? A case report and literature review.

Angelo Zarfati, Cristina Martucci, Alessandro Crocoli, Annalisa Serra, Giorgio Persano, Alessandro Inserra

Open access · goldFull text readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Angelo ZarfatiGeneral Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Cristina MartucciGeneral Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Alessandro CrocoliSurgical Oncology Unit, Department of Surgery, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Annalisa SerraHematology/Oncology Unit, Department of Pediatric Hematology/Oncology Cell and Gene Therapy, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Giorgio PersanoSurgical Oncology Unit, Department of Surgery, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Alessandro InserraGeneral Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Bambino Gesù Children's Hospital · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The second most common abdominal tumor in children is Wilms' tumor, and the lung is where it most often metastasizes. The typical metastases are multiple, peripherally located, round, and variable-sized nodules. Atypical patterns are also possible and may create diagnostic challenges, especially in patients treated with chemotherapy. Among these, cavitating metastases are an anecdotal type of atypical secondary lung lesions. Here, we report a case of a chemotherapy-induced cavitating Wilms' tumor pulmonary metastasis discovered during the follow-up for an anaplastic nephroblastoma in a 6-year-old girl. Furthermore, we conducted a review of the existing literature on this exceedingly rare radiological pattern to establish its best management.

Indexed as

atypical metastasiscavitationchemotherapycomputed-tomographylung metastasisnephroblastomapulmonary metastasisWilms’ tumor

Identifiers

PMID36925669
PMCPMC10011097
OpenAlexW4323319981

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read20
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.