Evidence map›Paper›PMID 36925488›Full record

ArticleIndian journal of psychological medicine2023

Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies.

Chittaranjan Andrade

Abstract read
In one paragraph

Article in Indian journal of psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Chittaranjan AndradeDept. of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0003-1526-567X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The previous article in this series explained basic concepts related to statistical signals and statistical noise in research. This article explains statistical noise in the context of randomized controlled trials (RCTs) and observational studies and offers suggestions on how noise in such studies may be reduced so as to better detect and understand the signal. Postrandomization bias related to RCTs and confounding in observational studies are discussed. Examples are provided to facilitate understanding.

Indexed as

confoundingnoiseobservational studiespostrandomization biasrandomized controlled trialsregressionSignal

Identifiers

PMID36925488
PMCPMC10011845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.