Evidence map›Paper›PMID 36925068›Full record

ArticleMucosal immunology2023

STAT4 increases the phenotypic and functional heterogeneity of intestinal tissue-resident memory T cells.

Helen Y Fung, Angie M Espinal, Matthew Teryek, Alexander D Lemenze, Tessa Bergsbaken

Open access · hybridAbstract read
In one paragraph

Article in Mucosal immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. CD8+ Tissue-Resident Memory T Cells: Versatile Guardians of the Tissue.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Helen Y FungCenter for Immunity and Inflammation, Department of Pathology, Laboratory Medicine & Immunology, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USA.
Angie M EspinalCenter for Immunity and Inflammation, Department of Pathology, Laboratory Medicine & Immunology, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USA.
Matthew TeryekCenter for Immunity and Inflammation, Department of Pathology, Laboratory Medicine & Immunology, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USA.
Alexander D LemenzeCenter for Immunity and Inflammation, Department of Pathology, Laboratory Medicine & Immunology, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USA.
Tessa BergsbakenCenter for Immunity and Inflammation, Department of Pathology, Laboratory Medicine & Immunology, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USA. Electronic address: t.bergsbaken@rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Tracie Saunders · 1997 to 2026
$94.5M
Differentiation and function of intestinal tissue-resident memory T cellsR01AI153096 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI BERGSBAKEN, TESSA · 2020 to 2024
$1.9M
Mobilization of tissue-resident lymphocytes during secondary infectionR21AI148900 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI BERGSBAKEN, TESSA · 2020 to 2021
$420k
NCI NIH HHS P30CA072720-5922NIAID NIH HHS R01 AI153096NIAID NIH HHS R21 AI148900
6 · The paper itself

Abstract

Tissue-resident memory T cells (Trms) are an important subset of lymphocytes that are lodged within non-lymphoid tissues and carry out diverse functions to control local pathogen replication. CD103 has been used to broadly define subsets of Trms within the intestine, with CD103

Indexed as

CD8-Positive T-LymphocytesImmunologic MemoryIntestinesMemory T CellsTransforming Growth Factor betaTransforming Growth Factor beta

Identifiers

PMID36925068
PMCPMC10327535
OpenAlexW4324367457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.