ArticleOphthalmology2023
Open-Globe Injury Repairs in the American Academy of Ophthalmology IRIS® Registry 2014 - 2018: Incidence, Risk Factors, and Visual Outcomes.
Article in Ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Long-term outcomes of nationwide coordinated neovascular AMD treatment: A study based on Polish national registry.Acta ophthalmologica · 2026Article
- Outpatient visits and secondary surgeries following open globe injuries: a single institution retrospective analysis.International ophthalmology · 2026Article
- Epidemiology of globe injury repair mechanisms in the TriNetX US collaborative network database: retrospective cohort study.BMC ophthalmology · 2025Article
- Associations between socioeconomic status and open globe injury.Eye (London, England) · 2025Article
- Letter to the Editor: Patterns and Prevention of Occupational Eye Injuries: A Narrative Review [Letter].Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Demographic and Clinical Factors Associated with Mechanisms of Open Globe Injury in the United States: A Multi-Center Study.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Ocular injuries among patients with major trauma in England and Wales from 2004 to 2021.Eye (London, England) · 2024Article
- A multi-center analysis of visual outcomes following open globe injury.Scientific reports · 2024Article
- Epidemiological and clinical characteristics of open globe injuries in Southwest China.Frontiers in medicine · 2024Article
- The global incidence and disability of eye injury: an analysis from the Global Burden of Disease Study 2019.EClinicalMedicine · 2023Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
purposeTo estimate incidence and evaluate demographic risk factors and visual acuity (VA) outcomes of open-globe injuries requiring surgical repair in the IRIS® Registry (Intelligent Research in Sight).
designRetrospective cohort study.
participantsPatients with open-globe injury repairs (OGRs) were identified by Current Procedural Terminology codes (65275, 65280, 65285, 65286, 65235, 65260, and 65265) from 2014 through 2018 in the IRIS Registry.
methodsLogistic regression models adjusting for age, sex, race, ethnicity, United States region, concurrent and subsequent surgeries, and baseline VA.
main outcome measuresOutcomes included annual and 5-year incidence rates per 100 000 people and factors associated with OGR, VA better than 20/40, and VA of 20/200 or worse at final follow-up (3-12 months after OGR).
resultsThirteen thousand seven hundred sixty-six OGRs were identified; 5-year cumulative incidence was 28.0 per 100 000 patients. Open-globe repair was associated with age 21 to 40 years compared with younger than 21 years (odds ratio [OR], 1.6; 95% confidence interval [CI], 1.5-1.7]), male sex (OR, 2.8; 95% CI, 2.7-2.9), Black versus White race (OR, 1.3; 95% CI, 1.2-1.4), Hispanic versus non-Hispanic ethnicity (OR, 1.7; 95% CI, 1.6-1.8), and South (OR, 1.4; 95% CI, 1.3-1.5) and West (OR, 1.3; 95% CI, 1.2-1.4) versus Midwest regions and associated inversely with Asian versus White race (OR, 0.6; 95% CI, 0.6-0.7). Visual acuity outcomes, analyzed in a subset of 2966 patients with VA data available, showed vision impairment (VA < 20/40) at final follow-up was associated with VA of 20/200 or worse at presentation (20/200 better than 20/40; OR, 11.1; 95% CI, 8.0-15.7), older age (e.g., > 80 years vs. < 21 years; OR, 5.8; 95% CI, 3.2-10.7), and Black versus White race (OR, 1.8; 95% CI, 1.3-2.6). Risk factors were similar for VA of 20/200 or worse after OGR. Among the 1063 patients undergoing OGR with VA of 20/200 or worse at presentation, VA did not improve to better than 20/200 at follow-up in 35% of patients (1063/2996).
conclusionsOur findings bring to light racial disparities in risk of OGR and poor visual outcomes that warrant further exploration. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references.
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