ArticleRespiratory medicine2023
Obstructive sleep apnea modulates clinical outcomes post-acute myocardial infarction: A large longitudinal veterans' dataset report.
Article in Respiratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- OSA and Acute Coronary Syndrome Severity: The Potential Role of Coronary Collateral Circulation.Chest · 2026Trial
- Obstructive Sleep Apnea in Myocardial Infarction: Paradoxical Cardioprotection, Chronic Detriment, and Unresolved Therapeutic Dilemmas.Sleep & breathing = Schlaf & Atmung · 2026Review
- Evaluation of an automated sleep apnea scoring algorithm via the Wesper Lab home sleep apnea test.Sleep medicine · 2026Article
- The Association between All-Cause Mortality and Obstructive Sleep Apnea in Adults: A U-Shaped Curve.Annals of the American Thoracic Society · 2025Article
- Impact of obstructive sleep apnea on inpatient outcomes of COVID-19: a propensity-score matching analysis of the US Nationwide Inpatient Sample 2020.Frontiers in medicine · 2025Article
- Genetic Factors Associated With Myocardial Infarction in Saudi Arabia.Journal of the Saudi Heart Association · 2025Review
- Personalizing Obstructive Sleep Apnea Therapy Using Machine Learning: Insights from the ISAACC Trial.Annals of the American Thoracic Society · 2024Article
- Identification of sleep phenotypes in COPD using machine learning-based cluster analysis.Respiratory medicine · 2024Observational
- Obesity paradox or hypoxia preconditioning: How obstructive sleep apnea modifies the Obesity-MI relationship.Sleep medicine · 2023Article
- Outcomes in Patients with Acute Myocardial Infarction and Known Sleep Apnea: A Nationwide Analysis.Journal of clinical medicine · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundWhile the longer-term Obstructive Sleep apnea (OSA)-related intermittent hypoxia (IH) leads to various comorbidities, it has become increasingly evident that OSA confers protective advantages during and after acute myocardial infarction (AMI). We hypothesized in patients who were admitted with acute MI, the presence of OSA is associated with lower in-hospital mortality compared to those without a prior diagnosis of OSA.
methodsIn this nationwide retrospective study utilizing Veterans Health Administration records, we included patients hospitalized for MI with a history of sleep disorders from 1999 to 2020. We divided patients into two cohorts: those with OSA and those without OSA. The primary outcome was in-hospital mortality during AMI hospitalization. We analyzed the data using logistic regression and calculated the odds ratio of in-hospital mortality.
resultsOut of more than four million veterans with any sleep diagnosis, 76,359 patients were hospitalized with a diagnosis of AMI. We observed 30,116 with OSA (age, 64 ± 10 years; BMI, 33 ± 7 kg/m
conclusionsPresence of OSA is associated with lower in-hospital mortality among patients admitted for AMI, after adjusting for various demographic and co-morbidity factors. This study highlights the complex relationship between OSA and cardiovascular health and highlights the need for further research in this area.
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