Evidence map›Paper›PMID 36923542›Full record

ArticleTheranostics2023

KLF5 inhibition potentiates anti-PD1 efficacy by enhancing CD8

Qi Wu, Zhou Liu, Zhijie Gao, Yao Luo, Fubing Li, ChuanYu Yang, Tiantian Wang, Xiangyu Meng, Haijun Chen, Juanjuan Li and 4 more

Open access · goldFull text read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

Qi WuKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Zhou LiuDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Zhijie GaoDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yao LuoMedical Faculty of Kunming University of Science and Technology, Kunming, China.
Fubing LiAcademy of Biomedical Engineering, Kunming Medical University, Kunming 650500, China.
ChuanYu YangKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Tiantian WangSchool of Life Science, University of Science & Technology of China, Hefei, 230027, Anhui, China.
Xiangyu MengCenter for Single-Cell Omics and Tumor Liquid Biopsy, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Haijun ChenCollege of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.
Juanjuan LiDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yanjie KongPathology department, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen 518035, China.
Chao DongDepartment of Medical Oncology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Si SunDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Ceshi ChenKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Wuhan University · CNChinese Academy of Sciences · CNKunming Medical University · CNFuzhou University · CNKunming University of Science and Technology · CNRenmin Hospital of Wuhan University · CNShenzhen Second People's Hospital · CNUniversity of Hong Kong · HKUniversity of Science and Technology of China · CNZhongnan Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DinoprostoneTranscription FactorsAnimalsCD8-Positive T-LymphocytesCell Line, TumorCyclooxygenase 2ImmunotherapyKruppel-Like Transcription FactorsMiceTumor MicroenvironmentCyclooxygenase 2DinoprostoneKlf5 protein, mouseKruppel-Like Transcription FactorsTranscription Factorsbreast cancerCD8+ T cellCOX2KLF5PD1 blocker

Identifiers

PMID36923542
PMCPMC10008740
OpenAlexW4324009871

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read43
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.