Evidence map›Paper›PMID 36923426›Full record

ArticleFrontiers in oncology2023

Clinicopathological characteristics and treatment outcome of resectable gastric cancer patients with small para-aortic lymph node.

Zhendan Yao, Hong Yang, Ming Cui, Jiadi Xing, Chenghai Zhang, Nan Zhang, Lei Chen, Fei Tan, Kai Xu, Maoxing Liu and 1 more

Open access · goldFull text read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Zhendan YaoKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Hong YangKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Ming CuiKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Jiadi XingKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Chenghai ZhangKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Nan ZhangKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Lei ChenKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Fei TanKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Kai XuKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Maoxing LiuKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Xiangqian SuKey laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital & Institute, Beijing, China.
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Resectable gastric cancer (GC) patients with small para-aortic lymph node (smaller than 10mm in diameter, sPAN) were seldom reported, and existing guidelines did not provide definite treatment recommendation for them. Methods: A total of 667 consecutive resectable GC patients were enrolled. 98 patients were in the sPAN group, and 569 patients without enlarged para-aortic lymph node were in the nPAN group. Standard D2 lymphadenectomy was performed. Neoadjuvant and adjuvant chemotherapy were administrated according to the cTNM and pTNM stage, respectively. Clinicopathological features and prognosis were compared between these two groups. Results: The median size of sPAN was 6 (range, 2-9) mm and the distribution was prevalent in No. 16b1. cN stage ( Conclusions: Standard D2 lymphadenectomy should be considered a valid approach for GC patients with sPAN associate to normal preoperative CEA and CA19-9 levels. Patients with sPAN associated to elevated CEA or CA19-9 levels could benefit from a multimodal approach: neoadjuvant chemotherapy; radical surgery with D2 plus lymph nodal dissection extended to No. 16 station.

Indexed as

carbohydrate antigen 19-9carcinoembryonic antigenD2 lymphadenectomygastric cancerpara-aortic lymph nodeprognosis

Identifiers

PMID36923426
PMCPMC10009175
OpenAlexW4322502825

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read68
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.