ArticleAnnals of translational medicine2023
The regularity of nourishing-yin prescription for treating ascites due to hepatitis B cirrhosis based on data mining technology.
Article in Annals of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors at 2 institutions in 1 country.
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Abstract
Background: Clinically, Chinese medicine is mostly used to treat ascites due to hepatitis B cirrhosis by nourishing-yin. We summarize the pattern of prescriptions for nourishing-yin inascites due to hepatitis B cirrhosis based on data mining to better use traditional Chinese medicine (TCM) to treat cirrhotic ascites in hepatitis B. Methods: Articles published from 2000 to 2020 on ascites due to hepatitis B cirrhosis were searched in the Chinese National Knowledge Infrastructure and Chinese Science and Technology Journal Database. The results of the search were screened and then treated as the data sources in turn. Based on the data sources, a prescription database of ascites due to hepatitis B cirrhosis was constructed. The data mining was conducted by statistical analysis of frequency and association. Core herbs, including the property and flavor, channel tropism, regularities of medicinal recipes, and core sets, among others, were examined. Results: Through combing 199 articles, a total of 201 prescriptions were selected, involving 138 kinds of herbs. The efficacy of cold herbs was slightly higher than that of warm herbs. The main flavors of herbs were sweet, bitter, and pungent. There were 30 herbs used ≥26 times in 201 prescriptions. The highest frequency of use was Conclusions: Through data mining, it was found that when TCM treats ascites due to hepatitis B cirrhosis, it attaches importance to using methods of tonifying deficiency and invigorating spleen for diuresis based on nourishing-yin to improve the clinical efficacy, which can provide reference for TCM's clinical use of nourishing-yin to treat ascites due to hepatitis B cirrhosis.
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