Evidence map›Paper›PMID 36923045›Full record

ArticleFrontiers in public health2023

The health impact of hazardous waste landfills and illegal dumps contaminated sites: An epidemiological study at ecological level in Italian Region.

Lucia Fazzo, Valerio Manno, Ivano Iavarone, Giada Minelli, Marco De Santis, Eleonora Beccaloni, Federica Scaini, Edoardo Miotto, Domenico Airoma, Pietro Comba

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Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lucia FazzoDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, Italy.
Valerio MannoStatistical Service, Istituto Superiore di Sanità, Rome, Italy.
Ivano IavaroneDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, Italy.
Giada MinelliStatistical Service, Istituto Superiore di Sanità, Rome, Italy.
Marco De SantisDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, Italy.
Eleonora BeccaloniDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, Italy.
Federica ScainiDepartment of Environment and Health, Istituto Superiore di Sanità, Rome, Italy.
Edoardo MiottoDepartment of Medicine, University of Udine, Udine, Italy.
Domenico AiromaAvellino Prosecution Office, Former North Naples Prosecution Office, Avellino, Italy.
Pietro CombaFellow, Collegium Ramazzini, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: The implementation of idoneous management of hazardous waste, in contrast to illegal practices, is one of the environment and health priorities of the WHO. The aim of the present study, based on a collaborative agreement between the Italian National Health Institute and a Prosecution Office located in Naples North, was to evaluate the health effects of illegal landfills and burning of urban and hazardous waste in the territory of the Prosecution Office. Methods: The municipalities included in the study territory were investigated with respect to the regional population. Regression analyses were performed in the study area between four classes of an environmental municipal indicator of waste risk (MRI) previously defined, computing the relative risks (RRs) in 2-4 MRI classes, with respect to the first MRI class (the least impacted). The prevalence of reproductive outcomes and cause-specific mortality and hospitalization were analyzed in the general population and in the 0-19-year-old population using SAS software. Results: An increase of mortality and hospitalization risk in both the genders of the whole area, with respect to regional population, were found for overall all cancer cases, cancer of the stomach, the liver, the lung and the kidney, and ischemic heart diseases. An increase of mortality for leukemias in the 0-19-year-old population and in hospitalization risk for certain conditions originating in the perinatal period were observed. Correlation between MRI and the risk of mortality from breast tumors in women (MRI class 2: RR = 1.06; MRI class 3: RR = 1.15; MRI class 4: RR = 1.11) and between MRI and the risk of hospitalization from testis tumors (MRI class 2: RR = 1.25; MRI class 3: RR = 1.31; MRI class 4: RR = 1.32) were found. The hospitalization risk from breast tumors and asthma exceeded significantly in both genders of three and four MRI classes. Among the 0-19-year-old population, correlation between MRI and hospitalization from leukemias (MRI class 2: RR = 1.48; MRI class 3: RR = 1.60; MRI class 4: RR = 1.41) and between MRI and the prevalence of preterm birth (MRI class 2: RR = 1.17; MRI class 3: RR = 1.08; MRI class 4: RR = 1.25) were found. Conclusion: A correlation between health outcomes and the environmental pressure by uncontrolled waste sites was found. Notwithstanding the limitation of the study, the results promote implementing the actions of environmental remediation and the prosecution of illegal practices.

Indexed as

Breast NeoplasmsLeukemiaPremature BirthAdolescentAdultChildChild, PreschoolEnvironmental ExposureEpidemiologic StudiesFemaleHazardous WasteHumansInfantInfant, NewbornItalyMaleHazardous Wastecancerdumpshazardous wastehospitalizationlandfillslow birth weightmortalitypreterm birth

Identifiers

PMID36923045
PMCPMC10010672

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