ArticleFrontiers in microbiology2023
Aculeaxanthones A-E, new xanthones from the marine-derived fungus
Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Assessment of antibacterial and anti-biofilm activities of marine fungal epiphytes associated with red and green algae of the Kenyan coast.Biotechnology notes (Amsterdam, Netherlands) · 2026Article
- Extracting Value from Marine and Microbial Natural Product Artifacts and Chemical Reactivity.Marine drugs · 2025Review
- Recent Advances in Secondary Metabolites from MarineMarine drugs · 2025Review
- Xanthone Dimers in Angiosperms, Fungi, Lichens: Comprehensive Review of Their Sources, Structures, and Pharmacological Properties.Molecules (Basel, Switzerland) · 2025Review
- Antimicrobial Potential of Secalonic Acids from Arctic-DerivedAntibiotics (Basel, Switzerland) · 2025Article
- Marine-derived fungi from the genusMycology · 2025Review
- Antibacterial properties of natural products from marine fungi reported between 2012 and 2023: a review.Archives of pharmacal research · 2024Review
- Significance of research on natural products from marine-derivedFrontiers in microbiology · 2024Review
- MarineMarine drugs · 2023Review
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Dimeric natural products are widespread in plants and microorganisms, which usually have complex structures and exhibit greater bioactivities than their corresponding monomers. In this study, we report five new dimeric tetrahydroxanthones, aculeaxanthones A-E ( Methods: A part of the culture was added to a total of 60 flasks containing 300 ml each of number II fungus liquid medium and culture 4 weeks in a static state at 28˚C. The liquid phase (18 L) and mycelia was separated from the fungal culture by filtering. A crude extract was obtained from the mycelia by ultrasound using acetone. To obtain a dry extract (18 g), the liquid phase combined with the crude extract were further extracted by EtOAc and concentrated in vacuo. The MIC of anaerobic bacteria was examined by a broth microdilution assay. To obtain MICs for aerobic bacteria, the agar dilution streak method recommended in Clinical and Laboratory Standards Institute document (CLSI) M07-A10 was used. Compounds 1-9 was tested against the Bel-7402, A-549 and HCT-116 cell lines according to MTT assay. Results and Discussion: The structures of these compounds were elucidated on the base of 1D and 2D NMR and HR-ESIMS data, and the absolute configurations of the new xanthones
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Registered trials
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