Evidence map›Paper›PMID 36922836›Full record

ArticleJournal of nanobiotechnology2023

Alleviating the hypoxic tumor microenvironment with MnO

Fen Pi, Xuanru Deng, Qian Xue, Lan Zheng, Hongxing Liu, Fang Yang, Tianfeng Chen

Open access · goldFull text read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Emerging Nanoplatforms are Effective Against Tumor Hypoxia.International journal of nanomedicine · 2026
    Review
  12. Biological Applications of Functionalized Cerium Oxide Nanoparticles.International journal of medical sciences · 2026
    Review
  13. Multifunctional CuFrontiers in chemistry · 2026
    Review
  14. Current Perspectives on Radiosensitizers in Cancer Radiotherapy.International journal of nanomedicine · 2026
    Review
  15. Lanthanide Nanotheranostics in Radiotherapy.International journal of molecular sciences · 2025
    Review
  16. Article
  17. Article
  18. Sericin-coated MnOScientific reports · 2025
    Article
  19. Article
  20. Enhancing Antioxidant and Cytotoxic Properties of CeONanomaterials (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fen Pi *Department of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China.
Xuanru Deng *Department of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China.
Qian XueDepartment of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China.
Lan ZhengDepartment of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China.
Hongxing LiuDepartment of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China. liuhongxing@gzhmu.edu.cn.
Fang YangDepartment of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China. tyoung@jnu.edu.cn.
Tianfeng ChenDepartment of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China.
Jinan University · CN

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2022A1515011664National Natural Science Foundation of China 82102083Science and Technology Plan Project of Guangzhou 202201020438
6 · The paper itself

Abstract

backgroundRadiotherapy is a commonly used tool in clinical practice to treat solid tumors. However, due to the unique microenvironment inside the tumor, such as high levels of GSH, overexpressed H

resultsTherefore, to further improve the efficiency of radiotherapy, a core-shell nanocomposite CeO

conclusionIn conclusion, the nanomaterial CeO

Indexed as

NanoparticlesNeoplasmsPhotochemotherapyRadiation-Sensitizing AgentsCell Line, TumorHumansHydrogen PeroxideHypoxiaMagnetic Resonance ImagingManganese CompoundsOxidesOxygenReactive Oxygen SpeciesTumor MicroenvironmentHydrogen PeroxideManganese CompoundsOxidesOxygenRadiation-Sensitizing AgentsReactive Oxygen SpeciesAntitumorCore–shell nanocompositeHypoxiaMR imagingRadiosensitizer

Identifiers

PMID36922836
PMCPMC10018832
OpenAlexW4324385933

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read36
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.