ArticleBMC genomics2023
Genetic diversity and signatures of selection in BoHuai goat revealed by whole-genome sequencing.
Article in BMC genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 24 citations in OpenAlex.
- Integrated SNP and SV Analyses Reveal Genetic Mechanisms Underlying High-Altitude Adaptation in Goats.Animals : an open access journal from MDPI · 2026Article
- ASAP1 gene InDel variants are associated with enhanced goat resistance against Brucella infection.Animal bioscience · 2026Article
- Reproductive Physiology, Genetic Architecture, and Management of Duolang Sheep Under Arid-Zone Production Systems: A Review.International journal of molecular sciences · 2026Review
- Progress on genome-wide association studies and selection signature analysis for agronomic traits in Chinese sheep and goats: review.Animal bioscience · 2026Article
- Integrative analysis of rumen microbiome and host metabolism reveals adaptive strategies of Boer goats to high-altitude environments.Frontiers in microbiology · 2026Article
- Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026Article
- Whole genome resequencing reveals genetic diversity, population structure, and selection signatures in local duck breeds.BMC genomics · 2025Article
- Genetic diversity and reproductive trait selection signal analysis of Bohuai goats based on whole genome sequencing.BMC genomics · 2025Article
- Genome-wide analysis provides insight into the genetic diversity and adaptability of Kazakhstan local goats.Scientific reports · 2025Article
- Whole-Genome Resequencing in Sheep: Applications in Breeding, Evolution, and Conservation.Genes · 2025Review
- Investigation of selection signatures of dairy goats using whole-genome sequencing data.BMC genomics · 2025Article
- Whole-genome resequencing reveals genetic diversity and selection signatures of Tongjiang and five goat breeds.Frontiers in veterinary science · 2025Article
- Genetic diversity, reproductive performance, and genetic enhancement strategies in Huang-Huai goats.Frontiers in genetics · 2025Review
- Examination of homozygosity runs and selection signatures in native goat breeds of Henan, China.BMC genomics · 2024Article
- Investigation of genetic diversity in the loach Misgurnus anguillicaudatus revealed by whole-genome resequencing.BMC genomics · 2024Article
- Genetic Diversity and Selection Signatures of Lvliang Black Goat Using Genome-Wide SNP Data.Animals : an open access journal from MDPI · 2024Article
- Whole-genome resequencing reveals new mutations in candidate genes for Beichuan-white goat prolificacya.Animal biotechnology · 2024Article
- Selection and Regulatory Network Analysis of Differential CircRNAs in the Hypothalamus of Goats with High and Low Reproductive Capacity.International journal of molecular sciences · 2024Article
- Genome-Wide Association Studies of Growth Trait Heterosis in Crossbred Meat Rabbits.Animals : an open access journal from MDPI · 2024Article
- Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat.Animals : an open access journal from MDPI · 2024Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundCross breeding is an important way to improve livestock performance. As an important livestock and poultry resource in Henan Province of China, Bohuai goat was formed by crossing Boer goat and Huai goat. After more than 20 years of breeding, BoHuai goats showed many advantages, such as fast growth, good reproductive performance, and high meat yield. In order to better develop and protect Bohuai goats, we sequenced the whole genomes of 30 BoHuai goats and 5 Huai goats to analyze the genetic diversity, population structure and genomic regions under selection of BoHuai goat. Furthermore, we used 126 published genomes of world-wide goat to characterize the genomic variation of BoHuai goat.
resultsThe results showed that the nucleotide diversity of BoHuai goats was lower and the degree of linkage imbalance was higher than that of other breeds. The analysis of population structure showed that BoHuai goats have obvious differences from other goat breeds. In addition, the BoHuai goat is more closely related to the Boer goat than the Huai goat and is highly similar to the Boer goat. Group by selection signal in the BoHuai goat study, we found that one region on chromosome 7 shows a very strong selection signal, which suggests that it could well be the segment region under the intense artificial selection results. Through selective sweeps, we detected some genes related to important traits such as lipid metabolism (LDLR, STAR, ANGPTL8), fertility (STAR), and disease resistance (CD274, DHPS, PDCD1LG2).
conclusionIn this paper, we elucidated the genomic variation, ancestry composition, and selective signals related to important economic traits in BoHuai goats. Our studies on the genome of BoHuai goats will not only help to understand the characteristics of the crossbred but also provide a basis for the improvement of cross-breeding programs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.