Evidence map›Paper›PMID 36922764›Full record

ArticleBMC nephrology2023

Pathological and clinical characteristics of late-onset oligomeganephronia based on a histomorphometric study.

Ya-Li Ren, Yang Li, Jie Gao, Xu-Jie Zhou, Li Yang, Su-Xia Wang

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ya-Li RenLaboratory of Electron Microscopy, Pathological Center, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, People's Republic of China.
Yang LiRenal Division, Department of Medicine, Institute of Nephrology, Key Laboratory of Renal Disease, Key Laboratory of CKD Prevention and Treatment, Peking University First Hospital, Peking University, Ministry of Health of China, Ministry of Education of China, Beijing, People's Republic of China.
Jie GaoDepartment of Clinical Laboratory, Tongji Shanxi Hospital, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Xu-Jie ZhouRenal Division, Department of Medicine, Institute of Nephrology, Key Laboratory of Renal Disease, Key Laboratory of CKD Prevention and Treatment, Peking University First Hospital, Peking University, Ministry of Health of China, Ministry of Education of China, Beijing, People's Republic of China.
Li YangRenal Division, Department of Medicine, Institute of Nephrology, Key Laboratory of Renal Disease, Key Laboratory of CKD Prevention and Treatment, Peking University First Hospital, Peking University, Ministry of Health of China, Ministry of Education of China, Beijing, People's Republic of China.
Su-Xia WangLaboratory of Electron Microscopy, Pathological Center, Peking University First Hospital, No. 8, Xishiku Street, Beijing, 100034, People's Republic of China. suxiawang@bjmu.edu.cn.
Peking University First Hospital · CNPeking University · CNShanxi Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLate-onset oligomeganephronia (OMN) is a rare chronic kidney disease and has no quantitative criteria for diagnosis yet. The current study aimed to explore its clinicopathological features by histomorphometric analysis.

methodsWe retrospectively re-reviewed all patients with enlarged and sparse glomeruli by light microscopy at Peking University First Hospital from 2012 to 2021, excluding those with any factor known to contribute to similar changes. Age- and sex-matched patients with thin basement membrane nephropathy were selected as control to establish the cut-off values for glomerulomegaly and rarity. Late-onset OMN cases were then confirmed and the clinicopathological characteristics were summarized.

resultsMean diameter and density of cortical glomeruli in control was 156.53 ± 27.50 μm and 4.07 ± 0.63 /mm

conclusionLate-onset OMN should be considered a special entity with relatively slow clinical progress characterized by hypertrophy of the sparsely distributed nephron.

Indexed as

Glomerulosclerosis, Focal SegmentalRenal Insufficiency, ChronicAdultFemaleHumansKidneyMaleProteinuriaRetrospective StudiesAdultChronic kidney diseaseGlomerulomegalyHistomorphometryOligomeganephronia

Identifiers

PMID36922764
PMCPMC10018837
OpenAlexW4324344307

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