Evidence map›Paper›PMID 36922639›Full record

ArticleScientific reports2023

The effect of 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) Addition on the physical characteristics of β-ionone liposomes.

Andang Miatmoko, Febe Harum Asmoro, Andre Alwi Azhari, Noorma Rosita, Chin-Shiu Huang

Open access · goldFull text read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Andang MiatmokoDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Airlangga, Campus C UNAIR, Surabaya, 60115, Indonesia. andang-m@ff.unair.ac.id.
Febe Harum AsmoroDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Airlangga, Campus C UNAIR, Surabaya, 60115, Indonesia.
Andre Alwi AzhariDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Airlangga, Campus C UNAIR, Surabaya, 60115, Indonesia.
Noorma RositaDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Airlangga, Campus C UNAIR, Surabaya, 60115, Indonesia.
Chin-Shiu HuangDepartment of Food Nutrition and Health Biotechnology, Asia University, Liofang Road, Wufeng District, Taichung, 413545, Taiwan.
Airlangga University · IDAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-ionone (ION) is a cyclic terpenoid compound that demonstrates considerable potential for the prevention and treatment of cancer. However, the water solubility of β-ionone is poor and the compound demonstrates low permeability. Liposomes have been reported as increasing both qualities. In this study, the development of β-ionone liposomes was initiated by adding 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) to produce cationic liposomes as a means of enhancing binding to cancer cells. Liposomes composed of β-ionone, HSPC, cholesterol, and DSPE-mPEG

Indexed as

LiposomesPropaneFatty Acids, MonounsaturatedHeLa CellsHumansNorisoprenoidsQuaternary Ammonium Compounds1,2-dioleoyloxy-3-(trimethylammonium)propanebeta-iononeFatty Acids, MonounsaturatedLiposomesNorisoprenoidsPropaneQuaternary Ammonium Compounds

Identifiers

PMID36922639
PMCPMC10017702
OpenAlexW4324344141

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read5
measurements read55
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.