Evidence map›Paper›PMID 36922494›Full record

ArticleNature communications2023

Structural basis of selective cannabinoid CB

Xiaoting Li, Hao Chang, Jara Bouma, Laura V de Paus, Partha Mukhopadhyay, Janos Paloczi, Mohammed Mustafa, Cas van der Horst, Sanjay Sunil Kumar, Lijie Wu and 9 more

Open access · goldFull text read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 67 citations in OpenAlex.

  1. (+)-Trans-Cannabidiol Is an Agonist at Human CBPharmacology research & perspectives · 2026
    Article
  2. Review
  3. Library Docking for Cannabinoid-2 Receptor Ligands.Journal of medicinal chemistry · 2026
    Article
  4. CNR1 and CNR2 Cannabinoid Receptor Mutations in Cancer Cells.Current issues in molecular biology · 2026
    Article
  5. Orally bioavailable CBResearch square · 2026
    Article
  6. Dynamic mechanism for subtype selectivity of endocannabinoids.The Journal of biological chemistry · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Library docking for Cannabinoid-2 Receptor ligands.bioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 3 countries.

Xiaoting Li *iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.ORCID 0000-0001-6431-3143
Hao Chang *iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.ORCID 0000-0003-1684-8201
Jara Bouma *Division of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden University, Oncode Institute, Leiden, the Netherlands.ORCID 0000-0002-6572-6158
Laura V de PausDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Oncode Institute, Leiden, the Netherlands.ORCID 0000-0002-5624-8457
Partha MukhopadhyayLaboratory of Cardiovascular Physiology and Tissue Injury, National Institute of Health/National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA.
Janos PalocziLaboratory of Cardiovascular Physiology and Tissue Injury, National Institute of Health/National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA.
Mohammed MustafaDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.
Cas van der HorstDivision of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden University, Oncode Institute, Leiden, the Netherlands.ORCID 0000-0002-5859-5348
Sanjay Sunil KumarDivision of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden University, Oncode Institute, Leiden, the Netherlands.ORCID 0000-0001-7386-5636
Lijie WuiHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Yanan YuiHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Richard J B H N van den BergDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Oncode Institute, Leiden, the Netherlands.
Antonius P A JanssenDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Oncode Institute, Leiden, the Netherlands.ORCID 0000-0003-4203-261X
Aron LichtmanDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.
Zhi-Jie LiuiHuman Institute, ShanghaiTech University, Shanghai, 201210, China. liuzhj@shanghaitech.edu.cn.ORCID 0000-0001-7279-2893
Pal PacherLaboratory of Cardiovascular Physiology and Tissue Injury, National Institute of Health/National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA. pacher@mail.nih.gov.ORCID 0000-0001-7036-8108
Mario van der SteltDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Oncode Institute, Leiden, the Netherlands. m.van.der.stelt@chem.leidenuniv.nl.ORCID 0000-0002-1029-5717
Laura H HeitmanDivision of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden University, Oncode Institute, Leiden, the Netherlands. l.h.heitman@lacdr.leidenuniv.nl.ORCID 0000-0002-1381-8464
Tian HuaiHuman Institute, ShanghaiTech University, Shanghai, 201210, China. huatian@shanghaitech.edu.cn.ORCID 0000-0002-6132-2068
Leiden University · NLShanghaiTech University · CNNational Institute on Alcohol Abuse and Alcoholism · USVirginia Commonwealth University · US

Funding

Mechanism of oxidative/nitrosative stress and inflammation-induced tissue injuryZIAAA000375 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI PACHER, PAL · 2009 to 2025
$27.8M
6 · The paper itself

Abstract

Cannabinoid CB

Indexed as

Cannabinoid Receptor AgonistsCannabinoidsCyclohexanolsReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Receptors, Cannabinoid3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanolCannabinoid Receptor AgonistsCannabinoidsCyclohexanolsHU 308Receptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Receptors, Cannabinoid

Identifiers

PMID36922494
PMCPMC10017709
OpenAlexW4324356294

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read203
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.