ArticleAutism : the international journal of research and practice2023
The earlier the better: An RCT of treatment timing effects for toddlers on the autism spectrum.
Article in Autism : the international journal of research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- The prevalence of autism in cerebellar malformations: a systematic review and meta-analysis.Journal of neurodevelopmental disorders · 2026Pooled it
- Examining the Transition from Single Words to Phrase Speech in Children with ASD: A Systematic Review.Clinical child and family psychology review · 2024Pooled it
- Trial
- The Language ENvironment Analysis (LENA) System in Toddlers With Early Indicators of Autism: Test-Retest Reliability and Convergent Validity With Clinical Language Assessments.Autism research : official journal of the International Society for Autism Research · 2025Trial
- The Impact of Using Standardized Autism Screening on Referral to Specialist Evaluation for Young Children on the Autism Spectrum: A Cluster-Randomized Controlled Trial.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Trial
- Exploring the Potential of Parent Report for Autism/Developmental Screening at the 18-Month Visit.Journal of autism and developmental disorders · 2026Article
- Failure points in the early autism identification pathway for children aged 0-5 years: Why screening is not diagnosis.Pediatric investigation · 2026Review
- Psychological Impact of Autism Screening on Caregivers.Autism research : official journal of the International Society for Autism Research · 2026Article
- Exploring the Potential of a Scenario-Based Approach to Early Autism Spectrum Disorder Screening.Psychiatry investigation · 2026Article
- Rising to the Challenge of Early Screening in Primary Health Care Through the Web Italian Network for Autism Spectrum Disorder (Win4ASD) in the Pediatric Population: Retrospective Observational Study.Journal of medical Internet research · 2026Observational
- Clinical and Sociodemographic Characteristics Associated with Access to Early Intervention Programs for Infants with Prodromes of Autism.Journal of clinical medicine · 2026Article
- Naturalistic facial dynamics enable quantitative clinical assessment of atypical expression phenotypes in children with autism spectrum disorder.NPJ digital medicine · 2026Article
- Navigating the Challenges: A Commentary on Barriers to Autism Screening in Childcare Centers.Behavioral sciences (Basel, Switzerland) · 2026Article
- The effectiveness of a community-based video-facilitated parenting intervention for child development integrated into routine maternal and child care services in India.PLOS global public health · 2026Article
- Feasibility and preliminary efficacy of an infant preemptive intervention for prodromes of autism spectrum disorder (ASD) delivered within an Italian tertiary hospital.Frontiers in child and adolescent psychiatry · 2026Article
- Developmental outcomes of young children with an autism diagnosis and its associated clinical correlates.Frontiers in psychiatry · 2026Article
- Parent-mediated early intervention in infants and toddlers at elevated likelihood for autism: a systematic review of randomized controlled trials.Frontiers in psychiatry · 2026Review
- Editorial: Very early identification and intervention for infants with prodromes of autism.Frontiers in psychiatry · 2026Article
- Development and validation of an early screening tool for young children with autism spectrum disorders: the checklist for Chinese toddlers with autism.Frontiers in psychiatry · 2026Article
- Expanding the toolkit: OPMs for studying the developing brain.Imaging neuroscience (Cambridge, Mass.) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
lay abstractBehavioral interventions that incorporate naturalistic, developmental strategies have been shown to improve outcomes for young children who receive an autism spectrum disorder (ASD) diagnosis. Although there is broad consensus that children on the spectrum should begin supports as soon as possible, the empirical evidence for this is relatively limited and little is known about the optimal age to start autism-specific interventions. Our team conducted a randomized controlled trial (RCT) to test the effects of starting intervention at different ages, using the Early Social Interaction (ESI) model, a parent-implemented intervention for toddlers on the spectrum. Participants included 82 autistic toddlers and their caregiver(s) who received 9 months of Individual-ESI
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.