ArticleLearning & memory (Cold Spring Harbor, N.Y.)2023
Sleep disruption by memory cues selectively weakens reactivated memories.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Concurrent Presentation of Memory-Related Odours and Sounds Nullified Sleep Reactivation Benefits.Journal of sleep research · 2026Article
- Random auditory stimulation during sleep disturbs traveling slow waves and declarative memory.iScience · 2026Article
- Creative problem-solving after experimentally provoking dreams of unsolved puzzles during REM sleep.Neuroscience of consciousness · 2026Article
- Targeted memory reactivation with sleep disruption does not weaken week-old memories.NPJ science of learning · 2024Article
- An update on recent advances in targeted memory reactivation during sleep.NPJ science of learning · 2024Review
- Improving memory via automated targeted memory reactivation during sleep.Journal of sleep research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A widely accepted view in memory research is that recently stored information can be reactivated during sleep, leading to memory strengthening. Two recent studies have shown that this effect can be reversed in participants with highly disrupted sleep. To test whether weakening of reactivated memories can result directly from sleep disruption, in this experiment we varied the intensity of memory reactivation cues such that some produced sleep arousals. Prior to sleep, participants (local community members) learned the locations of 75 objects, each accompanied by a sound naturally associated with that object. Location recall was tested before and after sleep, and a subset of the sounds was presented during sleep to provoke reactivation of the corresponding locations. Reactivation with sleep arousal weakened memories, unlike the improvement typically found after reactivation without sleep arousal. We conclude that reactivated memories can be selectively weakened during sleep, and that memory reactivation may strengthen or weaken memories depending on additional factors such as concurrent sleep disruption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.