ArticleJournal of the American Medical Informatics Association : JAMIA2023
Validation of an administrative algorithm for transgender and gender diverse persons against self-report data in electronic health records.
Article in Journal of the American Medical Informatics Association : JAMIA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- A Meta-Analysis of Sex-Based Differences in Health Service Use for Persons Living With Dementia Between 2018 and 2020 in Four Canadian Provinces.Journal of the American Geriatrics Society · 2026Pooled it
- Mental Health Therapy Utilization Among Transgender Medicare Beneficiaries, From 2011 to 2019.Medical care research and review : MCRR · 2026Article
- Intersectional HIV disparities among transgender Medicare beneficiaries of color.AIDS (London, England) · 2026Article
- Surgical and hormonal gender-affirming care: cross-domain determinants and artificial intelligence-enabled expansion.International journal for equity in health · 2026Review
- Prevalence and Incidence of Heart Failure Phenotypes Among Transgender and Gender-Diverse Adults in the United States.Journal of the American Heart Association · 2026Article
- A scoping review of models to identify transgender patients in electronic health records.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- When algorithms infer gender: revisiting computational phenotyping with electronic health records data.Biology of sex differences · 2025Review
- Sexual orientation, gender identity and cardiometabolic risk: a narrative review.Diabetologia · 2025Review
- Challenges and Best Practices Using Claims Data to Study Gender-Affirming Surgery in Transgender and Gender-Diverse Populations.American journal of public health · 2025Article
- Incident Atherosclerotic Cardiovascular Disease Among Veterans by Gender Identity: A Cohort Study.Journal of general internal medicine · 2025Article
- Cardiovascular Health at the Intersection of Race and Gender in Medicare Fee for Service.JAMA health forum · 2025Article
- Gender-affirming Hormone Therapy and Changes in Kidney Function in Adults: A Retrospective Population-based Study.Kidney medicine · 2025Article
- Chronic Conditions and Health Care Use Comparison Between Transgender/Gender Diverse and Cisgender Medicare Beneficiaries.Transgender health · 2025Article
- Gender-Affirming Surgery for Transgender and Gender Diverse Medicare Beneficiaries.JAMA network open · 2025Article
- Emergency department presentations by trans and gender diverse people in Sydney, Australia: Retrospective case series.Emergency medicine Australasia : EMA · 2025Article
- Chronic conditions among transgender Medicare beneficiaries: Variation by race, ethnicity, and Medicaid dual-enrollment.Disability and health journal · 2025Article
- Impact of Gender Identity Field in the Veterans Health Administration Electronic Health Record, 2016‒2023.American journal of public health · 2025Article
- Validating a Case Definition for Transgender Adults Using Administrative Data.JAMA network open · 2025Article
- Assessing how frailty and healthcare delays mediate the association between sexual and gender minority status and healthcare utilization in the All of Us Research Program.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Re: "Determining the Sex Assigned at Birth of Transgender and Nonbinary Populations in Administrative Claims Databases Utilizing Diagnostic and Procedure Codes" by Haley et al.Transgender health · 2024Article
Corrections and comments
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Authors and funding
13 authors at 9 institutions in 1 country.
Funding
Abstract
objectiveTo adapt and validate an algorithm to ascertain transgender and gender diverse (TGD) patients within electronic health record (EHR) data.
methodsUsing a previously unvalidated algorithm of identifying TGD persons within administrative claims data in a multistep, hierarchical process, we validated this algorithm in an EHR data set with self-reported gender identity.
resultsWithin an EHR data set of 52 746 adults with self-reported gender identity (gold standard) a previously unvalidated algorithm to identify TGD persons via TGD-related diagnosis and procedure codes, and gender-affirming hormone therapy prescription data had a sensitivity of 87.3% (95% confidence interval [CI] 86.4-88.2), specificity of 98.7% (95% CI 98.6-98.8), positive predictive value (PPV) of 88.7% (95% CI 87.9-89.4), and negative predictive value (NPV) of 98.5% (95% CI 98.4-98.6). The area under the curve (AUC) was 0.930 (95% CI 0.925-0.935). Steps to further categorize patients as presumably TGD men versus women based on prescription data performed well: sensitivity of 97.6%, specificity of 92.7%, PPV of 93.2%, and NPV of 97.4%. The AUC was 0.95 (95% CI 0.94-0.96).
conclusionsIn the absence of self-reported gender identity data, an algorithm to identify TGD patients in administrative data using TGD-related diagnosis and procedure codes, and gender-affirming hormone prescriptions performs well.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.