Evidence map›Paper›PMID 36920998›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2023

Insulin-induced vasoconstriction is prevalent in muscle microvasculature of otherwise healthy persons with type 1 diabetes.

Linda A Jahn, Lee M Hartline, Amanda J Kleiner, William B Horton, Farhad Hasan, Alvin Wai Kit Tan, Zhenqi Liu, Eugene J Barrett

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Linda A JahnDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.
Lee M HartlineDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.
Amanda J KleinerDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.
William B HortonDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0001-8081-1214
Farhad HasanDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.
Alvin Wai Kit TanDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.
Zhenqi LiuDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0001-5077-0941
Eugene J BarrettDivision of Endocrinology, Department of Medicine, University of Virginia, School of Medicine, Charlottesville, Virginia, United States.ORCID 0000-0003-0689-4044
University of Virginia · US

Funding

GLP-1R Regulation of Insulin ActionR01DK102359 · NIDDK · UNIVERSITY OF VIRGINIA · PI LIU, ZHENQI · 2015 to 2019
$2.8M
Acute effects of hyperglycemia on heart and skeletal muscle microvasculatureR01HL142250 · NHLBI · UNIVERSITY OF VIRGINIA · PI BARRETT, EUGENE JOSEPH · 2019 to 2022
$2.8M
Reversing vascular dysfunction in type 1 diabetesR01DK101944 · NIDDK · UNIVERSITY OF VIRGINIA · PI BARRETT, EUGENE JOSEPH · 2014 to 2017
$2.4M
NHLBI NIH HHS R01 HL142250NIDDK NIH HHS R01 DK101944NIDDK NIH HHS R01 DK102359
6 · The paper itself

Abstract

Insulin's microvascular actions and their relationship to insulin's metabolic actions have not been well studied in adults with type 1 diabetes mellitus (T1DM). We compared the metabolic and selected micro- and macrovascular responses to insulin by healthy adult control (

Indexed as

Diabetes Mellitus, Type 1Insulin ResistanceAdultBlood GlucoseGlucoseHumansInsulinMicrovesselsMuscle, SkeletalVasoconstrictionBlood GlucoseGlucoseInsulinendotheliummicrovascular insulin resistancetype 1 diabetes

Identifiers

PMID36920998
PMCPMC10125023
OpenAlexW4324309223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.