Evidence map›Paper›PMID 36920963›Full record

ArticlePloS one2023

Changes in clinical markers observed from pharmacist-managed cardiovascular risk reduction clinics in federally qualified health centers: A retrospective cohort study.

Jasmine D Gonzalvo, Ashley H Meredith, Sonak D Pastakia, Michael Peters, Madilyn Eberle, Andrew N Schmelz, Lauren Pence, Jessica S Triboletti, Todd A Walroth

Open access · goldFull text read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jasmine D GonzalvoPurdue University College of Pharmacy, Indianapolis, Indiana, United States of America.ORCID 0000-0001-8928-1432
Ashley H MeredithPurdue University College of Pharmacy, Indianapolis, Indiana, United States of America.ORCID 0000-0001-6162-8043
Sonak D PastakiaPurdue University College of Pharmacy, Indianapolis, Indiana, United States of America.
Michael PetersEskenazi Health, Indianapolis, Indiana, United States of America.ORCID 0000-0002-2652-5724
Madilyn EberlePurdue University College of Pharmacy, Indianapolis, Indiana, United States of America.
Andrew N SchmelzButler University College of Pharmacy and Health Sciences, Indianapolis, Indiana, United States of America.ORCID 0000-0002-5817-368X
Lauren PenceEskenazi Health, Indianapolis, Indiana, United States of America.
Jessica S TribolettiButler University College of Pharmacy and Health Sciences, Indianapolis, Indiana, United States of America.ORCID 0000-0002-6868-7369
Todd A WalrothEskenazi Health, Indianapolis, Indiana, United States of America.ORCID 0000-0001-6861-6408
University of Indianapolis · USEskenazi Health Foundation · USButler University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReductions in hemoglobin A1c (HbA1C) have been associated with improved cardiovascular outcomes and savings in medical expenditures. One public health approach has involved pharmacists within primary care settings. The objective was to assess change in HbA1C from baseline after 3-5 months of follow up in pharmacist-managed cardiovascular risk reduction (CVRR) clinics.

methodsThis retrospective cohort chart review occurred in eight pharmacist-managed CVRR federally qualified health clinics (FQHC) in Indiana, United States. Data were collected from patients seen by a CVRR pharmacist within the timeframe of January 1, 2015 through February 28, 2020. Data collected include: demographic characteristics and clinical markers between baseline and follow-up. HbA1C from baseline after 3 to 5 months was assessed with pared t-tests analysis. Other clinical variables were assessed and additional analysis were performed at 6-8 months. Additional results are reported between 9 months and 36 months of follow up.

resultsThe primary outcome evaluation included 445 patients. Over 36 months of evaluation, 3,803 encounters were described. Compared to baseline, HbA1C was reduced by 1.6% (95%CI -1.8, -1.4, p<0.01) after 3-5 months of CVRR care. Reductions in HbA1C persisted at 6-8 months with a reduction of 1.8% ([95%CI -2.0, -1.5] p<0.01). The follow-up losses were 29.5% at 3-5 months and 93.2% at 33-36 months.

conclusionsOur study augments the existing literature by demonstrating the health improvement of pharmacist-managed CVRR clinics. The great proportion of loss to follow-up is a limitation of this study to be considered. Additional studies exploring the expansion of similar models may amplify the public health impact of pharmacist-managed CVRR services in primary care sites.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2BiomarkersGlycated HemoglobinHeart Disease Risk FactorsHumansPharmacistsRetrospective StudiesRisk FactorsBiomarkersGlycated Hemoglobin

Identifiers

PMID36920963
PMCPMC10016666
OpenAlexW4324303503

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read66
identifiers read5
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.