Evidence map›Paper›PMID 36920918›Full record

ArticlePloS one2023

Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016-2018.

Peter N Fonjungo, Shirley Lecher, Clement Zeh, Erin Rottinghaus, Helen Chun, Christiane Adje-Toure, Spencer Lloyd, Jane W Mwangi, Michael Mwasekaga, Yohannes Mengistu Eshete and 18 more

Full text read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Peter N FonjungoDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.ORCID 0000-0002-6650-1751
Shirley LecherDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Clement ZehDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Erin RottinghausDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Helen ChunDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Christiane Adje-ToureDivision of Global HIV and TB, Center for Global Health, CDC, Abidjan, Côte d'Ivoire.
Spencer LloydDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Jane W MwangiDivision of Global HIV and TB, Center for Global Health, CDC, Nairobi, Kenya.
Michael MwasekagaDivision of Global HIV and TB, Center for Global Health, CDC, Dar es Salaam, Tanzania.
Yohannes Mengistu EsheteDivision of Global HIV and TB, Center for Global Health, CDC, Maseru, Lesotho.
Rituparna PatiDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Tsietso Mots'oaneLaboratory Services, Ministry of Health, Maseru, Lesotho.
Kiren MitrukaDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Anita BeukesNamibia Institute of Pathology, Windhoek, Namibia.
Christina MwangiDivision of Global HIV and TB, Center for Global Health, CDC, Kampala, Uganda.
Nancy BowenMinistry of Health, Nairobi, Kenya.
Ndapewa HamunimeMinistry of Health and Social Services, Windhoek, Namibia.
Rachel S BeardDivision of Global HIV and TB, Center for Global Health, CDC, Windhoek, Namibia.
Anyelwisye KabujeMinistry of Health, Dar es Salaam, Tanzania.
Susan NabaddaCentral Public Health Laboratories, Kampala, Uganda.
Andrew F AuldDivision of Global HIV and TB, Center for Global Health, CDC, Lilongwe, Malawi.ORCID 0000-0001-5089-9163
Shirish BalachandraDivision of Global HIV and TB, Center for Global Health, CDC, Abidjan, Côte d'Ivoire.
Innocent ZunguDivision of Global HIV and TB, Center for Global Health, CDC, Lilongwe, Malawi.
James KanduluMinistry of Health, Lilongwe, Malawi.
George AlemnjiOffice of the Global AIDS Coordinator and Health Diplomacy, U.S. Department of State, Washington, DC, United States of America.
Eboi EhuiMinistry of Health, Abidjan, Côte D'Ivoire.
Heather AlexanderDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.
Dennis EllenbergerDivision of Global HIV and TB, Center for Global Health, CDC, Atlanta, Georgia, United States of America.

Funding

PEPFAR
6 · The paper itself

Abstract

introductionWe assessed progress in HIV viral load (VL) scale up across seven sub-Saharan African (SSA) countries and discussed challenges and strategies for improving VL coverage among patients on anti-retroviral therapy (ART).

methodsA retrospective review of VL testing was conducted in Côte d'Ivoire, Kenya, Lesotho, Malawi, Namibia, Tanzania, and Uganda from January 2016 through June 2018. Data were collected and included the cumulative number of ART patients, number of patients with ≥ 1 VL test result (within the preceding 12 months), the percent of VL test results indicating viral suppression, and the mean turnaround time for VL testing.

resultsBetween 2016 and 2018, the proportion of PLHIV on ART in all 7 countries increased (range 5.7%-50.2%). During the same time period, the cumulative number of patients with one or more VL test increased from 22,996 to 917,980. Overall, viral suppression rates exceeded 85% for all countries except for Côte d'Ivoire at 78% by June 2018. Reported turnaround times for VL testing results improved in 5 out of 7 countries by between 5.4 days and 27.5 days.

conclusionsThese data demonstrate that remarkable progress has been made in the scale-up of HIV VL testing in the seven SSA countries.

Indexed as

Anti-HIV AgentsHIV InfectionsCote d'IvoireHumansMalawiRetrospective StudiesViral LoadAnti-HIV Agents

Identifiers

PMID36920918
PMCPMC10016655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.