ArticleJournal of applied clinical medical physics2023
A roadmap for implementation of kV-CBCT online adaptive radiation therapy and initial first year experiences.
Article in Journal of applied clinical medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed.
- HyperSight CBCT dose calculation accuracy for adaptive head and neck radiotherapy: Results from a prospective clinical trial.Medical physics · 2026Trial
- HyperSight CBCT image quality and metal artifact reduction for adaptive head and neck radiotherapy: Results from a prospective clinical trial.Journal of applied clinical medical physics · 2025Trial
- Improving deep learning organ segmentation accuracy in cone-beam CT-guided radiotherapy using a robust scatter suppression method.Physics and imaging in radiation oncology · 2026Article
- Dosimetric impact of daily skin surface variations in kidney stereotactic ablative proton therapy.Technical innovations & patient support in radiation oncology · 2026Article
- Automated planning architectures for online adaptive radiotherapy: A narrative review of the ethos and unity/Monaco platforms.Journal of applied clinical medical physics · 2026Review
- Development of CBCT-Guided Online Adaptive Radiotherapy.Cancers · 2026Review
- Article
- Adaptive Radiotherapy in the Era of Image Guidance and Artificial Intelligence: A Critical Review.Cancers · 2026Review
- Beyond Couch Correction in Head and Neck Radiotherapy: A Narrative Review of Action-Oriented Positioning Management.Cancers · 2026Review
- MRI-enhanced online adaptive radiotherapy by virtual integration of a standalone MRI simulator and CBCT-based treatment delivery.Radiation oncology (London, England) · 2026Article
- Dual-scan conformal cone-beam CT for targeted image-quality improvement using dynamic collimation.Journal of applied clinical medical physics · 2026Article
- Development of a cost-effective end-to-end commissioning test for simulation-omitted direct-to-unit adaptive radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Best Practice: CT-guided Adaptive Radiotherapy Reference Planning on the Ethos Platform.Journal of applied clinical medical physics · 2026Review
- Time toxicity in CBCT-guided radiation therapy: A retrospective analysis of unplanned imaging burden across disease sites.Technical innovations & patient support in radiation oncology · 2026Article
- Clinical experience with an online adaptive radiotherapy for prostate cancer: successful treatment time optimization.BMC cancer · 2026Article
- In-Silico Trial of Same-Day Simulation-Free Spatially Fractionated Adaptive Radiotherapy (SFJournal of applied clinical medical physics · 2026Article
- ART workflow based on CBCT and end-to-end clinical dynamic phantom validation.BMC medical imaging · 2026Article
- Early Experience Comparing Reduced Planning Target Volume Margins Using Cone Beam Computed Tomography Scan Guided Online Adaptive Radiation Therapy to Nonadaptive, Traditional Margin Plans for Muscle-Invasive Bladder Cancer.Advances in radiation oncology · 2026Article
- Seeing the invisible: In vivo dosimetry in radiotherapy with radiacoustic IMAGING.Medical physics · 2025Review
- Interfractional shifts of the carina and hilum during radiotherapy for non-small cell lung cancer: A retrospective study to identify associated factors.Journal of applied clinical medical physics · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
purposeOnline Adaptive Radiation Therapy (oART) follows a different treatment paradigm than conventional radiotherapy, and because of this, the resources, implementation, and workflows needed are unique. The purpose of this report is to outline our institution's experience establishing, organizing, and implementing an oART program using the Ethos therapy system.
methodsWe include resources used, operational models utilized, program creation timelines, and our institutional experiences with the implementation and operation of an oART program. Additionally, we provide a detailed summary of our first year's clinical experience where we delivered over 1000 daily adaptive fractions. For all treatments, the different stages of online adaption, primary patient set-up, initial kV-CBCT acquisition, contouring review and edit of influencer structures, target review and edits, plan evaluation and selection, Mobius3D 2nd check and adaptive QA, 2nd kV-CBCT for positional verification, treatment delivery, and patient leaving the room, were analyzed.
resultsWe retrospectively analyzed data from 97 patients treated from August 2021-August 2022. One thousand six hundred seventy seven individual fractions were treated and analyzed, 632(38%) were non-adaptive and 1045(62%) were adaptive. Seventy four of the 97 patients (76%) were treated with standard fractionation and 23 (24%) received stereotactic treatments. For the adaptive treatments, the generated adaptive plan was selected in 92% of treatments. On average(±std), adaptive sessions took 34.52 ± 11.42 min from start to finish. The entire adaptive process (from start of contour generation to verification CBCT), performed by the physicist (and physician on select days), was 19.84 ± 8.21 min.
conclusionWe present our institution's experience commissioning an oART program using the Ethos therapy system. It took us 12 months from project inception to the treatment of our first patient and 12 months to treat 1000 adaptive fractions. Retrospective analysis of delivered fractions showed that the average overall treatment time was approximately 35 min and the average time for the adaptive component of treatment was approximately 20 min.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.