Evidence map›Paper›PMID 36920800›Full record

ArticleEmerging microbes & infections2023

Inhalable vaccine of bacterial culture supernatant extract mediates protection against fatal pulmonary anthrax.

Li-Na Zhai, Yue Zhao, Xiao-Lin Song, Tong-Tong Qin, Zhi-Jun Zhang, Jia-Zhen Wang, Cheng-Yu Sui, Li-Li Zhang, Meng Lv, Ling-Fei Hu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Human anthrax vaccines: Current status and future prospects.Human vaccines & immunotherapeutics · 2025
    Review
  2. Anthrax meningoencephalitis: A case report.Experimental and therapeutic medicine · 2025
    Article
  3. Review
  4. Genes · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Li-Na ZhaiCollege of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Yue ZhaoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Xiao-Lin SongState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Tong-Tong QinState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Zhi-Jun ZhangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Jia-Zhen WangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Cheng-Yu SuiState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Li-Li ZhangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Meng LvState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Ling-Fei HuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Dong-Sheng ZhouState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Tong-Yu FangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Wen-Hui YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.
Yan-Chun WangState Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Institute of Microbiology · CNCzech Academy of Sciences, Institute of Biotechnology · CZGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary anthrax is the most fatal clinical form of anthrax and currently available injectable vaccines do not provide adequate protection against it. Hence, next-generation vaccines that effectively induce immunity against pulmonary anthrax are urgently needed. In the present study, we prepared an attenuated and low protease activity

Indexed as

AnthraxAnthrax VaccinesBacillus anthracisAnimalsAntibodies, BacterialAntigens, BacterialMicePeptide HydrolasesPowdersRespiratory Tract InfectionsVaccines, SyntheticAnthrax VaccinesAntibodies, BacterialAntigens, BacterialPeptide HydrolasesPowdersVaccines, Syntheticculture supernatant extractInhalable vaccinemucosal immune responseprotective antigenpulmonary anthrax

Identifiers

PMID36920800
PMCPMC10071900
OpenAlexW4324303369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.