ReviewPediatric nephrology (Berlin, Germany)2023
Antenatally detected urinary tract dilatation: long-term outcome.
Review in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Safely limiting the use of antibiotic prophylaxis and invasive testing in asymptomatic children with antenatally detected hydronephrosis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Fetal Hydronephrosis: A Narrative Review of Diagnostic Pathways, Prognostic Markers, and Management.Cureus · 2026Review
- Renal volumetry and functional impairment prediction in pediatric vesicoureteral reflux based on contrast-enhanced voiding urosonography.Quantitative imaging in medicine and surgery · 2026Article
- Voiding cystourethrography for the pediatric nephrologist: clinical value, challenges, and areas of debate.Pediatric nephrology (Berlin, Germany) · 2026Review
- Genetic diagnosis in fetal hydronephrosis: assessment using chromosomal microarray analysis and whole-genome sequencing.Human genomics · 2026Article
- Optimizing postnatal management based on prenatal UTD grading: a 5-year follow-up study of fetal hydronephrosis in a large Chinese cohort.BMC pediatrics · 2025Article
- Application of Ultrasound in Primary Vesicoureteral Reflux: From Diagnosis to Follow Up.Children (Basel, Switzerland) · 2025Review
- Increased kidney length in mild urinary tract dilatation is a significant prognostic factor for non-resolution.Pediatric nephrology (Berlin, Germany) · 2025Article
- Clinical Outcomes and Follow-Up in Children With Prenatally Detected Unilateral Ureteropelvic Junction Obstruction.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Morbidity in children with major kidney anomalies: a European population-based study.European journal of pediatrics · 2025Article
- Machine learning model for predicting urinary tract infection risk in febrile children under 3 years of age.Frontiers in pediatrics · 2025Article
- Swiss Consensus on Prenatal and Early Postnatal Urinary Tract Dilation: Practical Approach and When to Refer.Children (Basel, Switzerland) · 2024Review
- Maternal diseases and congenital anomalies of the kidney and urinary tract in offspring: a cohort study.World journal of pediatrics : WJP · 2024Article
- Antenatally detected urinary tract dilatation: a pediatric nephrologist's point of view.Childhood kidney diseases · 2024Review
- Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review provides updated knowledge on the long-term outcomes among children with antenatally diagnosed urinary tract dilatation (UTD), previously often referred to as antenatal hydronephrosis. Different definitions of UTD exist, which makes comparison between studies and generalized conclusions difficult. Roughly, one-third of antenatally diagnosed UTD, defined as a renal pelvis anterior posterior diameter (APD) of ≥ 4 mm in the second trimester and/or ≥ 7 mm in the third trimester, will resolve before birth, another third will resolve within the first years of life, and in the remaining cases, UTD will persist or a congenital abnormality (CAKUT) will be diagnosed postnatally. The risk of a postnatal CAKUT diagnosis increases with the degree of prenatal and postnatal dilatation, except for vesicoureteral reflux (VUR), which cannot be predicted from the degree of UTD. Urinary tract infections (UTIs) occur in 7-14% of children with UTD during the first years of life. The risk of UTI is higher in children with traditional risk factors for UTI, such as dilated VUR, hydroureteronephrosis, female gender, and intact foreskin. Continuous antibiotic prophylaxis may be considered in selected patients during the first years of life. In long-term follow-ups, permanent kidney damage is diagnosed in approximately 40% of children with moderate or severe UTD, but hypertension, proteinuria, and/or reduced eGFR are uncommon (0-5%). In children with mild UTD, the long-term outcome is excellent, and these children should not be subjected to unnecessary examinations and/or follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.