Evidence map›Paper›PMID 36920220›Full record

ArticleJournal of bacteriology2023

A Novel CovS Variant Harbored by a Colonization Strain Reduces Streptococcus pyogenes Virulence.

Céline Plainvert, Isabelle Rosinski-Chupin, Antonin Weckel, Clara Lambert, Gérald Touak, Elisabeth Sauvage, Claire Poyart, Philippe Glaser, Agnès Fouet

Abstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Céline PlainvertUniversité Paris Cité, Institut Cochin, INSERM, U1016, CNRS, UMR8104, Paris, France.
Isabelle Rosinski-ChupinInstitut Pasteur, Ecologie et Evolution de la Résistance aux Antibiotiques, UMR3525, Paris, France.
Antonin WeckelUniversité Paris Cité, Institut Cochin, INSERM, U1016, CNRS, UMR8104, Paris, France.
Clara LambertUniversité Paris Cité, Institut Cochin, INSERM, U1016, CNRS, UMR8104, Paris, France.
Gérald TouakService de Bactériologie, CNR des Streptocoques, Hôpitaux Universitaires Paris Centre, Paris, France.
Elisabeth SauvageInstitut Pasteur, Ecologie et Evolution de la Résistance aux Antibiotiques, UMR3525, Paris, France.
Claire PoyartUniversité Paris Cité, Institut Cochin, INSERM, U1016, CNRS, UMR8104, Paris, France.
Philippe GlaserInstitut Pasteur, Ecologie et Evolution de la Résistance aux Antibiotiques, UMR3525, Paris, France.
Agnès FouetUniversité Paris Cité, Institut Cochin, INSERM, U1016, CNRS, UMR8104, Paris, France.ORCID 0000-0001-7715-9157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcus pyogenes, also known as group A Streptococcus, causes a wide variety of diseases ranging from mild noninvasive to severe invasive infections. To identify possible causes of colonization-to-invasive switches, we determined the genomic sequences of 10 isolates from five pairs each composed of an invasive strain and a carriage strain originating from five infectious clusters. Among them, one pair displayed a single-nucleotide difference in

Indexed as

Streptococcal InfectionsStreptococcus pyogenesAnimalsBacterial ProteinsGene Expression Regulation, BacterialHistidine KinaseIntracellular Signaling Peptides and ProteinsMiceVirulenceVirulence FactorsBacterial ProteinsHistidine KinaseIntracellular Signaling Peptides and ProteinsVirulence FactorsadaptationcovRSenvironmental signalgroup A Streptococcusinfectiontwo-component regulatory system

Identifiers

PMID36920220
PMCPMC10127592

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.