ReviewClinical microbiology reviews2023
Congenital Syphilis: a Review of Global Epidemiology.
Review in Clinical microbiology reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Neurosyphilis-Induced Psychosis in Europe: A Systematic Review of Case Reports.Pathogens (Basel, Switzerland) · 2024Pooled it
- Computational methods applied to syphilis: where are we, and where are we going?Frontiers in public health · 2023Pooled it
- Trial
- Congenital Syphilis in Brazil: Municipal Antenatal Care, Primary Health Care Capacity, and Territorial Inequalities, 2015-2024.Maternal and child health journal · 2026Article
- Gestational and congenital syphilis in a Brazilian harbor city: A population-based study of prevalence, determinants, and adverse neonatal outcomes.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases · 2026Article
- Re-Emergence of the Great Mimicker: Congenital Syphilis in a Low Prevalence Setting.Infectious disease reports · 2026Article
- The Congenital Syphilis Surge: Clinician Lessons to Turn the Rising Tide.Advances in pediatrics · 2026Review
- Congenital Syphilis Elimination in Latin America: A Systematic Analysis of Policy and Progress.Sexually transmitted diseases · 2026Article
- Article
- Trends in Congenital Syphilis Cases by Maternal Country of Birth, Spain, 2016-2024.Emerging infectious diseases · 2026Article
- Maternal and congenital syphilis in Fiji 2019-2022: a secondary analysis of clinical trial data.Epidemiology and infection · 2026Article
- The neglected role of partner treatment in congenital syphilis control in Brazil: nationwide evidence from 2007 to 2023.Lancet regional health. Americas · 2026Article
- [Dual Test in Pregnant Women: Case of a General Zone Hospital with Family Medicine].Revista medica del Instituto Mexicano del Seguro Social · 2026Observational
- First-year dynamics of the plasma virome and cytokine profile in infants born to mothers with syphilis.Journal of translational medicine · 2026Article
- "As long as you are married you cannot protect yourself against syphilis": qualitative exploration of syphilis risk perception and antenatal care seeking among pregnant women in Uganda.BMC public health · 2026Article
- Characteristics and effectiveness of maternal health interventions to prevent mother-to-child transmission (PMTCT) of syphilis in a global setting: a scoping review using Intervention Mapping as a framework.BMC pregnancy and childbirth · 2026Article
- Gestational syphilis and prenatal care: a study in light of individual, social, and programmatic vulnerabilities.Revista da Escola de Enfermagem da U S P · 2026Article
- Participatory development of strategies to combat congenital syphilis: action research.Revista latino-americana de enfermagem · 2026Article
- Case Report: Congenital syphilis presenting with respiratory symptoms in an infant.Frontiers in pediatrics · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2007, the World Health Organization (WHO) launched a global health initiative for the elimination of mother-to-child transmission (MTCT) of syphilis. This condition is highly preventable through antenatal identification of syphilis infection and treatment with penicillin during pregnancy. This review summarizes the global status of MTCT of syphilis and concludes that this condition remains a significant issue worldwide. There are large variations in case rates by region, with the highest numbers of cases in the African and Eastern Mediterranean regions, where there are also the least data available. There are also pockets of high-incidence areas within the other regions. Although the general trend is of decreasing rates over time, there are concerning indications of consistently increasing congenital syphilis cases in some areas, particularly in areas which have previously had very low case numbers. A concerted effort will be required to achieve the 2007 WHO goal of worldwide elimination of MTCT of syphilis in the near future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.