Evidence map›Paper›PMID 36920074›Full record

ArticleACS infectious diseases2023

MAT Gain of Activity Mutation in

Mu Feng, Hilda Namanja-Magliano, Saranathan Rajagopalan, Tanmay Mishra, Rodrigo G Ducati, Brett M Hirsch, Libusha Kelly, Wendy Szymczak, Jorge Eduardo Fajardo, Simone Sidoli and 3 more

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Mu FengDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Hilda Namanja-MaglianoDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Saranathan RajagopalanDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Tanmay MishraDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Rodrigo G DucatiDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.ORCID 0000-0002-8783-8847
Brett M HirschDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Libusha KellyDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Wendy SzymczakDepartment of Pathology, Montefiore-Einstein Medical Center, Bronx, New York 10467, United States.
Jorge Eduardo FajardoDepartment of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York 10461, United States.ORCID 0000-0001-9701-8546
Simone SidoliDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Andras FiserDepartment of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Vern L SchrammDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.ORCID 0000-0002-8056-1929
Albert Einstein College of Medicine · USMontefiore Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2M
TRANSITION STATE ANALYSIS OF ENZYMATIC REACTIONSR01GM041916 · NIGMS · YESHIVA UNIVERSITY · PI SCHRAMM, VERN L. · 1989 to 2023
$10.0M
Molecular Genetic Analysis of Mycobacterium TuberculosisR37AI026170 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI WILLIAM Robert JACOBS · 2004 to 2026
$7.7M
MOLECULAR GENETIC ANALYSIS OF MYCOBACTERIUM TUBERCULOSISR01AI026170 · NIAID · YESHIVA UNIVERSITY · PI JACOBS, WILLIAM ROBERT · 1989 to 2022
$7.1M
Molecular basis of recognition in the Immunological SynapseR35GM136357 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI FISER, ANDRAS · 2020 to 2024
$2.7M
Interdisciplinary protein engineering approach to design high affinity antibodies for flavivirusesR01AI141816 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FISER, ANDRAS · 2019 to 2023
$2.1M
Orbitrap Exploris 480 Basic SystemS10OD030286 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SIDOLI, SIMONE · 2021 to 2021
$600k
TB Phage therapy: Optimizing delivery methods of mycobacteriophages to target intracellular Mycobacterium tuberculosisR21AI156853 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI JACOBS, WILLIAM ROBERT · 2021 to 2022
$462k
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA013330NIAID NIH HHS R01 AI026170NIAID NIH HHS R01 AI141816NIAID NIH HHS R21 AI156853NIAID NIH HHS R37 AI026170NIGMS NIH HHS R01 GM041916NIGMS NIH HHS R35 GM136357NIH HHS S10 OD030286
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Helicobacter pyloriHumansN-Glycosyl HydrolasesPurine-Nucleoside Phosphorylase5'-methylthioadenosine phosphorylaseN-Glycosyl HydrolasesPurine-Nucleoside Phosphorylaseantibiotic resistanceflagella synthesisfutalosine menaquinone pathwaygastric ulcersiron transportS-adenosylmethionine

Identifiers

PMID36920074
PMCPMC10311514
OpenAlexW4324311367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.