Evidence map›Paper›PMID 36919673›Full record

ReviewCell transplantation

Stem Cells: Recent Developments Redefining Epilepsy Therapy.

Adam Alayli, Gavin Lockard, Jonah Gordon, Jacob Connolly, Molly Monsour, Samantha Schimmel, Ike Dela Peña, Cesar V Borlongan

Abstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam AlayliUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.ORCID 0000-0002-6986-788X
Gavin LockardUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Jonah GordonUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.ORCID 0000-0002-9161-5160
Jacob ConnollyUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Molly MonsourUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Samantha SchimmelUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Ike Dela PeñaDepartment of Pharmaceutical and Administrative Sciences, Loma Linda University, Loma Linda, CA, USA.ORCID 0000-0003-2046-522X
Cesar V BorlonganCenter of Excellence for Aging and Brain Repair, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.ORCID 0000-0002-2966-9782

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of stem cell therapy is growing rapidly and hopes to offer an alternative solution to diseases that are historically treated medically or surgically. One such focus of research is the treatment of medically refractory epilepsy, which is traditionally approached from a surgical or interventional standpoint. Research shows that stem cell transplantation has potential to offer significant benefits to the epilepsy patient by reducing seizure frequency, intensity, and neurological deficits that often result from the condition. This review explores the basic science progress made on the topic of stem cells and epilepsy by focusing on experiments using animal models and highlighting the most recent developments from the last 4 years.

Indexed as

EpilepsyStem Cell TransplantationSeizuresStem Cellsepilepsyneurological diseasestem cell therapy

Identifiers

PMID36919673
PMCPMC10021095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.