Evidence map›Paper›PMID 36919130›Full record

ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2023

Effect of Moderate Intensity Continuous Training and Slow Type Interval Training to Gene Expression of TGF-β in Type 2 Diabetes Mellitus Model Wistar Rats.

Muhammad Syahputra, Dharma Lindarto, Oke Rina Ramayani, Yetty Machrina, Ambrosius Purba, Imam Budi Putra, Iqbal Pahlevi Adeputra Nasution, Juliandi Harahap

Open access · greenAbstract read
In one paragraph

Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Muhammad SyahputraPhilosophy Doctor In Medicine Programme, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Dharma LindartoDepartment of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Oke Rina RamayaniDepartment of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Yetty MachrinaDepartment of Physiology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Ambrosius PurbaDepartment of Physiology, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia.
Imam Budi PutraDepartment of Dermatology and Venerology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Iqbal Pahlevi Adeputra NasutionDepartment of Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Juliandi HarahapDepartment of Community Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
University of North Sumatra · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Physical exercise is a process of increasing contraction of skeletal muscles involving several organ systems to increase energy formation and it is one of the pillars for the management of type 2 diabetes mellitus (TDM2). T2DM affects the expression of the TGF-β gene. Objective: This study aims to determine the effect of moderate intensity continuous training and slow interval training in expression of TGF-β gene in wistar rats T2DM model. Methods: A moderate intensity continuous training physical activity given to the diabetic rat group in the form of running on a treadmill with a running speed of 20 m/min for 30 minutes while the slow type interval training physical activity given to the diabetic rat group was in the form of running on a treadmill with a running speed of 20 m/minute for 10 repetition sessions, with a duration of 2 minutes per session with interspersed active breaks for 1 minute. TGF-β gene expression was measured using real-time methods. Results: The results in the continuous group, TGF-β significant decreased p < 0.05. In the interval group, TGF- β insignificant decreased p > 0.05. Moderate intensity continuous training was insignificantly better at decreasing the expression of the TGF-β genes. Conclusion: This research concluded that there is an effect of moderate intensity continuous training and slow interval training on the expression of TGF-β genes in wistar rats T2DM.

Indexed as

Diabetes Mellitus, Type 2Physical Conditioning, AnimalAnimalsGene ExpressionRatsRats, WistarTransforming Growth Factor betaTransforming Growth Factor betacontinuous traininginterval trainingratsTGF- βtype 2 diabetes mellitus

Identifiers

PMID36919130
PMCPMC10008258
OpenAlexW4321455408

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.