Evidence map›Paper›PMID 36918796›Full record

ArticleBMC cancer2023

A nomogram based on platelet-to-lymphocyte ratio for predicting pathological complete response of breast cancer after neoadjuvant chemotherapy.

Rulan Ma, Wanzhen Wei, Haixia Ye, Chengxue Dang, Kang Li, Dawei Yuan

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Article in BMC cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Nomogram Prediction of Response to Neoadjuvant Chemotherapy Plus Pembrolizumab in Locally Advanced Hypopharyngeal Squamous Cell Carcinoma.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rulan MaDepartment of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Shannxi, 710061, Xi'an, China.
Wanzhen WeiDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Shannxi, 710061, Xi'an, China.
Haixia YeThe Second Clinical College, Department of Medicine, Wuhan University, Hubei, 430071, Wuhan, China.
Chengxue DangDepartment of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Shannxi, 710061, Xi'an, China.
Kang LiDepartment of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Shannxi, 710061, Xi'an, China. healthlee@xjtu.edu.cn.
Dawei YuanDepartment of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Shannxi, 710061, Xi'an, China. dwyuan@mail.xjtu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the role of platelet-to-lymphocyte ratio (PLR) in complete pathological response (pCR) of breast cancer (BC) patients after neoadjuvant chemotherapy (NAC), as well as to establish and validate a nomogram for predicting pCR.

methodsBC patients diagnosed and treated in the First Affiliated Hospital of Xi'an Jiaotong University from January 2019 to June 2022 were included. The correlation between pCR and clinicopathological characteristics was analyzed by Chi-square test. Logistic regression analysis was performed to evaluate the factors that might affect pCR. Based on the results of regression analysis, a nomogram for predicting pCR was established and validated.

resultsA total of 112 BC patients were included in this study. 50.89% of the patients acquired pCR after NAC. Chi-square test showed that PLR was significantly correlated with pCR (X

conclusionPLR, PLT, WBC and tumor grade were independent predictors of pCR in BC patients after NAC. The nomogram based on the above positive factors showed a good predictive ability.

Indexed as

Breast NeoplasmsNeoadjuvant TherapyNomogramsAdultAgedBlood PlateletsFemaleHumansLymphocytesMiddle AgedPrognosisRetrospective StudiesBreast cancerNeoadjuvant chemotherapyNomogramPathological complete responsePrediction model

Identifiers

PMID36918796
PMCPMC10015959

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