Evidence map›Paper›PMID 36918635›Full record

ArticleScientific reports2023

Association between the early mobilization of mechanically ventilated patients and independence in activities of daily living at hospital discharge.

Shinichi Watanabe, Jun Hirasawa, Yuji Naito, Motoki Mizutani, Akihiro Uemura, Shogo Nishimura, Yasunari Morita, Yuki Iida

Open access · goldFull text readMulticenter Study
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Early mobilisation practices in Windhoek intensive care units: A retrospective review of patient profiles and physiotherapy practice.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Patient perceptions of ICU physiotherapy: 'Your body needs to go somewhere to be recharged … '.The Southern African journal of critical care : the official journal of the Critical Care Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Shinichi WatanabeDepartment of Rehabilitation Medicine, National Hospital Organization, Nagoya Medical Center, 4-1-1 Sannomaru, Naka-ku, Nagoya, Aichi, 460-0001, Japan. billabonghonor@yahoo.co.jp.
Jun HirasawaDepartment of Rehabilitation Medicine, Tosei General Hospital, Seto, Aichi, Japan.
Yuji NaitoDepartment of Rehabilitation Medicine, National Hospital Organization, Shizuoka Medical Center, Nagasawa, Shimizu, Suntougun, Shizuoka, Japan.
Motoki MizutaniDepartment of Rehabilitation Medicine, Ichinomiyanishi Hospital, Kaimeitaira, Itinomiya, Aichi, Japan.
Akihiro UemuraDepartment of Rehabilitation, Toyohashi Municipal Hospital, Hachikennishi, Aotake, Toyohashi, Aichi, Japan.
Shogo NishimuraDepartment of Rehabilitation Medicine, Kainan Hospital, Namihonden, Maegasu, Yatomi, Aichi, Japan.
Yasunari MoritaDepartment of Emergency Medicine, National Hospital Organization, Nagoya Medical Center, Sannomaru, Nakaku, Nagoya, Aichi, Japan.
Yuki IidaDepartment of Physical Therapy, School of Health Sciences, Toyohashi Sozo University, 20-1 Matushita, Ushikawa-cho, Toyohashi, Aichi, 440-8511, Japan. y2iida@na.commufa.jp.
National Hospital Organization · JPIchinomiya Kenshin College · JPKinan Hospital · JPNagoya Medical Center · JPTosei General Hospital · JPToyohashi Municipal Hospital · JPToyohashi Sozo College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical dysfunction after discharge from the intensive care unit (ICU) is recognized as a common complication among ICU patients. Early mobilization (EM), defined as the ability to sit on the edge of the bed within 5 days, may help improve physical dysfunction. However, the barriers to, and achievement of, EM and their impact on physical dysfunction have not been fully investigated. This study aimed to investigate the achievement of EM and barriers to it and their impact on patient outcomes in mechanically ventilated ICU patients. We conducted this multicenter retrospective cohort study by collecting data from six ICUs in Japan. Consecutive patients who were admitted to the ICU between April 2019 and March 2020, were aged ≥ 18 years, and received mechanical ventilation for > 48 h were eligible. The primary outcome was the rate of independent activities of daily living (ADL), defined as a score ≥ 70 on the Barthel index at hospital discharge. Daily changes in barriers of mobilization, including consciousness, respiratory, circulatory, medical staff factors, and device factors (catheter, drain, and dialysis), along with the clinical outcomes were investigated. The association among barriers, mobilization, and Barthel index ≥ 70 was analyzed using multivariable logistic regression analysis. During the study period, 206 patients were enrolled. EM was achieved in 116 patients (68%) on the fifth ICU day. The primary outcome revealed that achieving EM was associated with a Barthel index ≥ 70 at hospital discharge [adjusted odds ratio (AOR), 3.44; 95% confidence interval (CI), 1.70-6.96]. Device factors (AOR, 0.31; 95% CI, 0.13-0.75, respectively) were significantly associated with EM achievement. EM was associated with independent ADL at hospital discharge. Time to first mobilization and barriers to achieving mobilization can be important parameters for achieving ADL independence at discharge. Further research is required to determine the most common barriers so that they can be identified and removed.

Indexed as

Activities of Daily LivingRespiration, ArtificialEarly AmbulationHospitalsHumansIntensive Care UnitsPatient DischargeRenal DialysisRetrospective Studies

Identifiers

PMID36918635
PMCPMC10015081
OpenAlexW4324309827

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read24
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.