Evidence map›Paper›PMID 36918629›Full record

ReviewEye (London, England)2023

The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS).

Sean Ming Sheng Ng, Rebecca Low, Clara Pak, SerSei Lai, Bernett Lee, Peter McCluskey, Richard Symes, Alessandro Invernizzi, Edmund Tsui, Ranju Kharel Sitaula and 16 more

Abstract readReview
In one paragraph

Review in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Sean Ming Sheng NgLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Rebecca LowDepartment of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.
Clara PakUniversity of Rochester School of Medicine & Dentistry, Rochester, NY, USA.
SerSei LaiDepartment of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.
Bernett LeeLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Peter McCluskeySave Sight Institute, The University of Sydney, Sydney, NSW, Australia.
Richard SymesSave Sight Institute, The University of Sydney, Sydney, NSW, Australia.
Alessandro InvernizziSave Sight Institute, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0003-3400-1987
Edmund TsuiStein Eye Institute, David Geffen of Medicine at UCLA, Los Angeles, CA, USA.ORCID 0000-0001-7532-9191
Ranju Kharel SitaulaDepartment of Ophthalmology, B. P. Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
Muna KharelNepal Army Institute of Health Sciences, Kathmandu, Nepal.
Anadi KhatriBirat Eye Hospital, Biratnagar, Nepal.ORCID 0000-0002-0444-224X
Anna Nur UtamiJakarta Eye Centre, Jakarta, Indonesia.
Rina La Distia NoraUniversitas Indonesia, West Java, Indonesia.
Ikhwanuliman PuteraUniversitas Indonesia, West Java, Indonesia.ORCID 0000-0002-9350-5133
Alok SenSadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India.ORCID 0000-0003-2374-4187
Manisha AgarwalDepartment of Ophthalmology, Dr Shroff's Charity Eye Hospital Daryaganj, New Delhi, India.
Padmamalini MahendradasDepartment of Uveitis and Ocular Immunology, Narayana Nethralaya, Bangalore, India.
Jyotirmay BiswasDepartment of Ophthalmology, Sankara Nethralaya, Chennai, India.ORCID 0000-0003-1214-5429
Carlos PavesioMoorfields Eye Hospital, NHS Foundation Trust, London, UK.
Luca CiminoDepartment of Surgery, Medicine Dentistry and Morphological Sciences with Interest in Transplant, University of Modena and Reggio Emilia, Modena, Italy.
Lucia SobrinDepartment of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Schepens Eye Research Institute, Boston, MA, USA.
John H KempenDepartment of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Schepens Eye Research Institute, Boston, MA, USA.ORCID 0000-0002-2967-4792
Vishali GuptaAdvanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rupesh AgrawalLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. rupesh_agrawal@ttsh.com.sg.ORCID 0000-0002-6662-5850
OASIS Study Group

Funding

MOH | National Medical Research Council (NMRC) NMRC/CSAINV/19nov-007
6 · The paper itself

Abstract

In the current literature, clinical registry cohorts related to ocular inflammation are few and far between, and there are none involving multi-continental international data. Many existing registries comprise administrative databases, data related to specific uveitic diseases, or are designed to address a particular clinical problem. The existing data, although useful and serving their intended purposes, are segmented and may not be sufficiently robust to design prognostication tools or draw epidemiological conclusions in the field of uveitis and ocular inflammation. To solve this, we have developed the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) Clinical Registry. OASIS collects prospective and retrospective data on patients with all types of ocular inflammatory conditions from centers all around the world. It is a primarily web-based platform with alternative offline modes of access. A comprehensive set of clinical data ranging from demographics, past medical history, clinical presentation, working diagnosis to visual outcomes are collected over a range of time points. Additionally, clinical images such as optical coherence tomography, fundus fluorescein angiography and indocyanine green angiography studies may be uploaded. Through the capturing of diverse, well-structured, and clinically meaningful data in a simplified and consistent fashion, OASIS will deliver a comprehensive and well organized data set ripe for data analysis. The applications of the registry are numerous, and include performing epidemiological analysis, monitoring drug side effects, and studying treatment safety efficacy. Furthermore, the data compiled in OASIS will be used to develop new classification and diagnostic systems, as well as treatment and prognostication guidelines for uveitis.

Indexed as

InflammationUveitisFluorescein AngiographyHumansMulticenter Studies as TopicProspective StudiesRetrospective StudiesTomography, Optical Coherence

Identifiers

PMID36918629
PMCPMC10564879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.