ReviewJournal of endocrinological investigation2023
Bone quality in endocrine diseases: determinants and clinical relevance.
Review in Journal of endocrinological investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Hypoparathyroidism: Musculoskeletal Manifestations Related to Parathormone Deficiency.Current rheumatology reviews · 2024Pooled it
- Palopegteriparatide for adults with chronic hypoparathyroidism: skeletal dynamics through 3 years of the phase 2 PaTH forward trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Trial
- Editorial for the Special Issue Entitled "Novel Aspects of Endocrine Care: From Patient-Centered Management of Endocrine Diseases to Guidelines Standards".Journal of clinical medicine · 2026Article
- Body composition in male hypogonadism: practical considerations to the use of dual-energy x-ray absorptiometry.Reviews in endocrine & metabolic disorders · 2026Review
- Bone mineral density and trabecular bone score in adults with primary immunodeficiencies: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Endocrine-related osteoporosis: bone quality, clinical phenotype, and targeted management.Frontiers in endocrinology · 2026Review
- Osteoporosis and Fracture Risk in Ovarian Cancer: Beyond the Oncologic Burden.Diagnostics (Basel, Switzerland) · 2025Review
- Acromegaly treatment and bone: a bidirectional relationship.Pituitary · 2025Review
- Trabecular bone score as a possible new surgical recommendation in patients with asymptomatic primary hyperparathyroidism.Journal of endocrinological investigation · 2025Article
- A practical use of bone turnover markers in management of patients with skeletal fragility.Endocrine · 2025Review
- Assessment of Mandibular Bone Architecture in Patients with Endocrine Disorders Using Fractal Dimension and Histogram Analysis.Tomography (Ann Arbor, Mich.) · 2025Article
- Associations between Per- and Polyfluoroalkyl Substances Exposures and Bone Mineral: A Systematic Review and Best Evidence Synthesis.Environment & health (Washington, D.C.) · 2025Article
- Mild Hyponatremia Is Not Associated With Degradation of Trabecular Bone Microarchitecture Despite Bone Mass Loss.The Journal of clinical endocrinology and metabolism · 2025Article
- Hypercalcemia Following Adrenalectomy for Cushing Syndrome in a Patient with Post-Surgical Hypoparathyroidism.Diseases (Basel, Switzerland) · 2025Article
- Contradictory links between lipid levels and bone health: atherogenic index of plasma and bone microarchitecture.Journal of orthopaedic surgery and research · 2025Article
- Lightweight deep learning system for automated bone age assessment in Chinese children: enhancing clinical efficiency and diagnostic accuracy.Frontiers in endocrinology · 2025Article
- Cushing's disease and bone.Pituitary · 2024Review
- Differential effects of teriparatide, denosumab and zoledronate on hip structural and mechanical parameters in osteoporosis; a real-life study.Journal of endocrinological investigation · 2024Article
- Role of bisphosphonates in osteoporosis caused by adult growth hormone deficiency.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Review
- The direct impact of pegvisomant on osteoblast functions and bone development.Journal of endocrinological investigation · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBone is one of the main targets of hormones and endocrine diseases are frequent causes of secondary osteoporosis and fractures in real-world clinical practice. However, diagnosis of skeletal fragility and prediction of fractures in this setting could be a challenge, since the skeletal alterations induced by endocrine disorders are not generally captured by dual-energy X-ray absorptiometry (DXA) measurement of bone mineral density (BMD), that is the gold standard for diagnosis of osteoporosis in the general population. The aim of this paper is to review the existing evidence related to bone quality features in endocrine diseases, proposing assessment with new techniques in the future.
methodsA comprehensive search within electronic databases was performed to collect reports of bone quality in primary hyperparathyroidism, hypoparathyroidism, hyperthyroidism, hypercortisolism, growth hormone deficiency, acromegaly, male hypogonadism and diabetes mellitus.
resultsUsing invasive and non-invasive techniques, such as high-resolution peripheral quantitative computed tomography or DXA measurement of trabecular bone score (TBS), several studies consistently reported altered bone quality as predominant determinant of fragility fractures in subjects affected by chronic endocrine disorders.
conclusionsAssessment of skeletal fragility in endocrine diseases might take advantage from the use of techniques to detect perturbation in bone architecture with the aim of best identifying patients at high risk of fractures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.