ArticleBMJ open2023
Sequential Organ Failure Assessment (SOFA) Score for predicting mortality in patients with sepsis in Vietnamese intensive care units: a multicentre, cross-sectional study.
Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed, 52 citations in OpenAlex.
- Predictive validity of daily sequential organ failure assessment (SOFA)-2 score for 30-day mortality.Critical care (London, England) · 2026Observational
- Elastic functional Cox regression model with shape predictors.Journal of applied statistics · 2026Article
- Outcomes and mortality predictors after tracheostomy in intensive care unit patients with infectious diseases: A 5-year retrospective cohort study from Brazil.Scientific reports · 2026Article
- Admission-day SOFA-2 versus SOFA for mortality discrimination: external validation in a large multicenter ICU database.Critical care (London, England) · 2026Article
- The effects of high-protein vs conventional protein enteral nutrition on intestinal permeability, severity of disease, and mortality in critically ill intensive care unit Patients: Protocol for a randomized controlled trial.Contemporary clinical trials communications · 2026Article
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- Integration of Systemic Immune-Inflammation Index and Lactate for diagnostic and early risk stratification in pediatric sepsis.BMC infectious diseases · 2026Article
- A clinically interpretable prediction model for acute mortality in patients with pneumonia requiring mechanical ventilation.Respiratory research · 2026Article
- Development and temporal validation of SCRAPS scoring tool to predict poor prognosis in gram negative sepsis patients requiring early intensive care or high dependency unit admission.BMC infectious diseases · 2026Observational
- Development and evaluation of predictive performance of "organ failure assessment by ratio score" to predict sepsis mortality in Indian intensive care unit patients: An observational study.Indian journal of anaesthesia · 2026Article
- Article
- Comparative Prognostic Performance of SOFA2.0 and SOFA for 28-Day Mortality in Patients Developing Sepsis During ECMO Support.Journal of inflammation research · 2026Article
- Validation of CRownLab Pneumoplex for the Detection ofInternational journal of microbiology · 2026Article
- Nephrocast-V: A Deep Learning Model for the Prediction of Vancomycin Trough Concentration Using Electronic Health Record Data.Pharmacotherapy · 2026Article
- Article
- A Novel Composite Bioscore Integrating Biomarkers, Clinical Scores, and Comorbidity Indices for Prognostic Stratification in Sepsis.Journal of inflammation research · 2026Article
- Bimodal regulation and precision therapy of neutrophil extracellular traps in liver ischemia-reperfusion injury: recent advances.Frontiers in immunology · 2026Review
- Predictive validity of the simplified Radiographic Assessment of Lung Edema score for mortality in critically ill patients with COVID-19.Frontiers in medicine · 2026Article
- The SOFA score as a mortality predictor in ICU patients: insights from a tertiary care hospital in Pakistan.BMC research notes · 2025Article
- Impact of Neutropenia on Clinical Outcomes in Critically Ill Patients with Acute Respiratory Failure.Pulmonary therapy · 2025Article
Corrections and comments
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Authors and funding
27 authors at 12 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the accuracy of the Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation II (APACHE II) Scores in predicting mortality among intensive care unit (ICU) patients with sepsis in a low-income and middle-income country.
designA multicentre, cross-sectional study.
settingA total of 15 adult ICUs throughout Vietnam.
participantsWe included all patients aged ≥18 years who were admitted to ICUs for sepsis and who were still in ICUs from 00:00 to 23:59 of the specified study days (ie, 9 January, 3 April, 3 July and 9 October of the year 2019). PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was hospital all-cause mortality (hospital mortality). We also defined the secondary outcome as all-cause deaths in the ICU (ICU mortality).
resultsOf 252 patients, 40.1% died in hospitals, and 33.3% died in ICUs. SOFA Score (areas under the receiver operating characteristic curve (AUROC): 0.688 (95% CI 0.618 to 0.758); cut-off value≥7.5; P
conclusionsIn this study, SOFA and APACHE II Scores were worthwhile in predicting mortality among ICU patients with sepsis. However, due to better discrimination for predicting ICU mortality, the SOFA Score was preferable to the APACHE II Score in predicting mortality.Clinical trials registry - India: CTRI/2019/01/016898.
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