Trial reportThe Thoracic and cardiovascular surgeon2024
Confirmation of Safety of Titanium Wire in Sternotomy Closure, A Randomized Prospective Study.
Trial report in The Thoracic and cardiovascular surgeon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- Ultra-High-Molecular-Weight Polyethylene Cables for Sternal Closure in a Metal-Allergic Patient With Stanford Type A Acute Aortic Dissection: A Case Report.Clinical case reports · 2026Article
- Clinical outcomes of a novel sternal closure technique using tension-fixed titanium cables and a biodegradable poly-lactic acid mesh plate.Journal of cardiothoracic surgery · 2026Article
- Stainless Steel Versus Titanium Miniplates in the Treatment of Mandibular Fractures: A Comparative Study.Cureus · 2025Article
- Postoperative C-reactive protein levels correlate with reduced spinal column mobility after median sternotomy: a prospective cohort study.Journal of thoracic disease · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are many factors that are known to increase the risk of sternal wound infection (SWI); some studies have reported that nickel is a risk factor for SWI. Titanium wires have only been used as an alternative to steel wires in patients with known allergy to nickel. However, there is a paucity of literature regarding the safety of using titanium wires compared to that on the safety of steel wires for sternum closure after cardiac surgery. Therefore, this study aimed to demonstrate the noninferiority of titanium wires, even in patients without a known allergy.
methodsA total of 322 patients who underwent elective full median sternotomy were randomly assigned to sternal closure either by titanium wires (
resultsFourteen patients had sternal instability, six (3.7%) patients in the titanium group and eight (5%) patients in the stainless steel group (
conclusionTitanium wires are a good alternative and have been proven to be safe and effective for sternal closure. The surgeon should be aware of the possibility of developing an allergic reaction to the wires, especially in patients with previous multiple allergic histories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.