Evidence map›Paper›PMID 36918067›Full record

ArticleThe Journal of hospital infection2023

Establishment and application of test methodology demonstrating the functionality of air purification systems in reducing virus-loaded aerosol in indoor air.

J M B M van der Vossen, A P Kreikamp, V Hatt, A M T Ouwens, D J Brasem, M Heerikhuisen, R C Montijn

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of hospital infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

J M B M van der VossenDepartment of Microbiology and Systems Biology, The Netherlands Organisation for Applied Scientific Research TNO, Leiden, the Netherlands. Electronic address: jos.vandervossen@tno.nl.
A P KreikampDepartment of Microbiology and Systems Biology, The Netherlands Organisation for Applied Scientific Research TNO, Leiden, the Netherlands.
V HattDepartment of Microbiology and Systems Biology, The Netherlands Organisation for Applied Scientific Research TNO, Leiden, the Netherlands.
A M T OuwensDepartment of Microbiology and Systems Biology, The Netherlands Organisation for Applied Scientific Research TNO, Leiden, the Netherlands.
D J BrasemDepartment of Microbiology and Systems Biology, The Netherlands Organisation for Applied Scientific Research TNO, Leiden, the Netherlands.
M HeerikhuisenDepartment of Microbiology and Systems Biology, The Netherlands Organisation for Applied Scientific Research TNO, Leiden, the Netherlands.
R C MontijnDepartment of Microbiology and Systems Biology, The Netherlands Organisation for Applied Scientific Research TNO, Leiden, the Netherlands.
Netherlands Organisation for Applied Scientific Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global COVID-19 pandemic has resulted in a greater interest in improving the ventilation of indoor environments in order to remove aerosolized virus and thus reduce transmission. Air purification systems have been proposed as a solution to improve aerosol removal.

aimThe aim was to determine the efficacy of air purification systems in reducing the viral load in the environmental air of a room.

methodsA containment room equipped with HEPA filter on air intake and exhaust was constructed. It was connected via an inlet with the BSL-2 facility. From the BSL-2, Feline Coronavirus (FCoV)-loaded aerosols were released into the containment room. After nebulization, air sampling was performed to determine the viral load in air prior to assessing the clean air delivery rate of the air purification systems. The infectivity of the captured viruses was also examined.

findingsThe air purification systems realized a 97-99% reduction in viral load in air in 1 h. Captured infectious FCoV was reduced by 99.9%-99.99% by use of an ESP technology.

conclusionsThe air purification systems, using ESP technology or HEPA filter, reduce the viral load in air. The ESP purifiers inactivate captured FCoV viruses. Therefore, air purification systems can be used as an adjunctive infection control measure.

Indexed as

Air Pollution, IndoorCOVID-19AnimalsCatsHumansInfection ControlPandemicsRespiratory Aerosols and DropletsAerosolAir purificationBacteriophageClean air delivery rateCOVID-19Virus

Identifiers

PMID36918067
PMCPMC10008183
OpenAlexW4323980727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.