Evidence map›Paper›PMID 36918066›Full record

Observational studyOphthalmology. Glaucoma

Comparison of Perimetric Outcomes from a Tablet Perimeter, Smart Visual Function Analyzer, and Humphrey Field Analyzer.

Joyce Kang, Sofia De Arrigunaga, Sandra E Freeman, Yan Zhao, Michael Lin, Daniel L Liebman, Ana M Roldan, Julia A Kim, Dolly S Chang, David S Friedman and 1 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Ophthalmology. Glaucoma. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Portable perimetry devices for glaucoma patients -practicality in daily clinical practice and glaucoma expert assessment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Joyce KangOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts.
Sofia De ArrigunagaOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts.
Sandra E FreemanOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts.
Yan ZhaoOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts.
Michael LinOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts.
Daniel L LiebmanOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts.
Ana M RoldanDepartment of Ophthalmology, Penn State College of Medicine, Hershey, Pennsylvania.
Julia A KimGenentech Inc., South San Francisco, California.
Dolly S ChangGenentech Inc., South San Francisco, California; Stanford University School of Medicine, Palo Alto, California.
David S FriedmanOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts.
Tobias ElzeOphthalmology, Massachusetts Eye and Ear, Boston, Massachusetts. Electronic address: tobias_elze@meei.harvard.edu.
Massachusetts Eye and Ear Infirmary · USPalo Alto University · USPenn State Milton S. Hershey Medical Center · US

Funding

VISION RESEARCHP30EY003790 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI Patricia Ann D'Amore · 1985 to 2026
$25.5M
Personalizing Glaucoma Diagnosis by Disease Specific Patterns and Individual Eye AnatomyR01EY030575 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI ELZE, TOBIAS · 2019 to 2023
$2.4M
NEI NIH HHS P30 EY003790NEI NIH HHS R01 EY030575
6 · The paper itself

Abstract

purposeThe tablet-based Melbourne Rapid Fields (MRF) visual field (VF) test and the IMOvifa Smart Visual Function Analyzer (SVFA) are portable perimeters that may allow for at-home monitoring and more frequent testing. We compared tablet and SVFA results with outputs from the Humphrey Field Analyzer (HFA) 24-2 Swedish Interactive Threshold Algorithm Standard program.

designObservational cross-sectional study. SUBJECTS: Adult participants with a diagnosis of glaucoma, suspected glaucoma, or ocular hypertension seen in the Massachusetts Eye and Ear glaucoma clinic were enrolled. All participants were reliable and experienced HFA testers.

methodsParticipants were tested with the SVFA and HFA. The study staff also trained participants on the MRF tablet with instructions to take weekly tests at home for 3 months. Visual field results from the 3 devices were compared.

main outcome measuresMean deviation (MD), pattern standard deviation (PSD), reliability parameters, and point sensitivity.

resultsOverall, 79 participants (133 eyes) with a mean age of 61 ± 13 years (range, 26-79 years) were included; 59% of the participants were female, and the mean HFA MD was -2.7 ± 3.9 dB. The global indices of MD and PSD did not significantly vary between HFA and the 2 novel devices, except that the tablet VF reported a 0.6 dB higher PSD compared with HFA. However, tablet and SVFA sensitivities significantly differed from those of the HFA at 36 and 39 locations, respectively, out of 52 locations. Relative to HFA, the tablet overestimated light sensitivity in the nasal field while underestimating the temporal field. The SVFA generally underestimated light sensitivity, but its results were more similar to HFA results compared with the tablet.

conclusionsAlthough average MD values from the 2 novel devices suggest that they provide similar results to the HFA, point-by-point comparisons highlight notable deviations. Differences in specific point sensitivity values were significant, especially between the tablet and the other 2 devices. These differences may in part be explained by differences in the devices' normative databases as well as how MD is calculated. However, the tablet had substantial differences based on location, indicating that the tablet design itself may be responsible for differences in local sensitivities. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

GlaucomaOcular HypertensionAdultAgedFemaleHumansMaleMiddle AgedPhotophobiaReproducibility of ResultsVisual FieldsVisual Field TestsAt-Home MonitoringGlaucomaPerimetryTelemedicineVisual field

Identifiers

PMID36918066
PMCPMC10495534
OpenAlexW4323977315

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.