Evidence map›Paper›PMID 36917789›Full record

ArticleAmerican journal of respiratory cell and molecular biology2023

Novel Loss-of-Function

Alba Vera-Zambrano, Mauro Lago-Docampo, Natalia Gallego, Juan Felipe Franco-Gonzalez, Daniel Morales-Cano, Alejandro Cruz-Utrilla, Marta Villegas-Esguevillas, Edgar Fernández-Malavé, Pilar Escribano-Subías, Jair Antonio Tenorio-Castaño and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Functional characterisation ofThe European respiratory journal · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Editorial: Therapeutics in pulmonary arterial hypertension.Frontiers in cardiovascular medicine · 2024
    Article
  12. Revisiting the Role of KCNA5 in Pulmonary Arterial Hypertension.American journal of respiratory cell and molecular biology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Alba Vera-ZambranoDepartment of Pharmacology and Toxicology and.ORCID 0000-0002-4040-1920
Mauro Lago-DocampoCentro de Investigación en Nanomateriais e Biomedicina (CINBIO), Universidade de Vigo, Vigo, Spain.ORCID 0000-0002-8799-6079
Natalia GallegoInstitute of Medical and Molecular Genetics-IdiPAZ, Universitary Hospital La Paz, University Autonoma of Madrid, Madrid, Spain.
Juan Felipe Franco-GonzalezDepartment of Structural and Chemical Biology, Margarita Salas Center for Biological Research, Scientific Research Council, Madrid, Spain.
Daniel Morales-CanoExperimental Pathology of Atherosclerosis Laboratory, National Center for Cardiovascular Research Carlos III, Madrid, Spain.ORCID 0000-0002-1692-4633
Alejandro Cruz-UtrillaCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, and.ORCID 0000-0002-3851-4037
Marta Villegas-EsguevillasDepartment of Pharmacology and Toxicology and.
Edgar Fernández-MalavéDepartment of Immunology, Ophthalmology and ENT, School of Medicine, University Complutense of Madrid, Madrid, Spain.
Pilar Escribano-SubíasCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, and.
Jair Antonio Tenorio-CastañoInstitute of Medical and Molecular Genetics-IdiPAZ, Universitary Hospital La Paz, University Autonoma of Madrid, Madrid, Spain.
Francisco Perez-VizcainoDepartment of Pharmacology and Toxicology and.ORCID 0000-0001-6309-7418
Diana ValverdeCentro de Investigación en Nanomateriais e Biomedicina (CINBIO), Universidade de Vigo, Vigo, Spain.
Teresa GonzálezDepartment of Biochemistry, School of Medicine, University Autonoma of Madrid, Madrid, Spain.
Spanish group of Ion Channels in Pulmonary Hypertension (SICPH) investigatorsDepartment of Pharmacology and Toxicology and.
Angel CogolludoDepartment of Pharmacology and Toxicology and.ORCID 0000-0002-1382-1698

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduced expression and/or activity of Kv1.5 channels (encoded by

Indexed as

Hypertension, PulmonaryPulmonary Arterial HypertensionFamilial Primary Pulmonary HypertensionHEK293 CellsHumansKv1.5 Potassium ChannelPulmonary ArteryKCNA5 protein, humanKv1.5 Potassium Channelion channelsKCNA5 variantsKv1.5potassium channelspulmonary hypertension

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.