Evidence map›Paper›PMID 36917782›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2023

Do People With Apraxia of Speech and Aphasia Improve or Worsen Across Repeated Sequential Word Trials?

Katarina L Haley, Adam Jacks, Jessica D Richardson, Tyson G Harmon, Elizabeth H Lacey, Peter Turkeltaub

Open access · greenAbstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in psychology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Katarina L HaleyDivision of Speech and Hearing Sciences, Department of Allied Health Sciences, The University of North Carolina at Chapel Hill.ORCID 0000-0002-1158-2160
Adam JacksDivision of Speech and Hearing Sciences, Department of Allied Health Sciences, The University of North Carolina at Chapel Hill.ORCID 0000-0001-6358-2878
Jessica D RichardsonDepartment of Speech and Hearing Sciences, The University of New Mexico, Albuquerque.ORCID 0000-0003-2769-3014
Tyson G HarmonDepartment of Communication Disorders, Brigham Young University, Provo, UT.ORCID 0000-0003-1936-8668
Elizabeth H LaceyDepartment of Neurology, Georgetown University Medical Center, and MedStar National Rehabilitation Hospital, Washington, DC.ORCID 0000-0002-9389-0211
Peter TurkeltaubDepartment of Neurology, Georgetown University Medical Center, and MedStar National Rehabilitation Hospital, Washington, DC.ORCID 0000-0003-2080-6055
MedStar National Rehabilitation Hospital · USUniversity of North Carolina at Chapel Hill · USBrigham Young University · USUniversity of New Mexico · US

Funding

University of New Mexico (UNM) Center for Brain Recovery and RepairP20GM109089 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI RICHARDSON, JESSICA D · 2015 to 2024
$22.7M
Institutional Career Development CoreKL2TR001432 · NCATS · GEORGETOWN UNIVERSITY · PI UMANS, JASON G · 2015 to 2024
$7.5M
Contributions of spared brain structures and connections to aphasia recoveryR01DC014960 · NIDCD · GEORGETOWN UNIVERSITY · PI TURKELTAUB, PETER ETHAN · 2017 to 2021
$4.0M
Targeted Transcranial Electrotherapy to accelerate Stroke Rehabilitation-Exploratory Trial on AphasiaR44NS092144 · NINDS · SOTERIX MEDICAL,INC. · PI DATTA, ABHISHEK, PARRA, LUCAS C · 2015 to 2018
$3.0M
Speech profiles and cue responsiveness in primary progressive aphasiaR01DC018569 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HALEY, KATARINA L · 2020 to 2024
$2.8M
Auditory masking effects on speech fluency in aphasia and apraxia of speechR03DC011881 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JACKS, ADAM PATRICK · 2012 to 2014
$422k
NCATS NIH HHS KL2 TR001432NIDCD NIH HHS R01 DC014960NIDCD NIH HHS R01 DC018569NIDCD NIH HHS R03 DC011881NIGMS NIH HHS P20 GM109089NINDS NIH HHS R44 NS092144
6 · The paper itself

Abstract

purposeDuring motor speech examinations for suspected apraxia of speech (AOS), clients are routinely asked to repeat words several times sequentially. The purpose of this study was to understand the task in terms of the relationship among consecutive attempts. We asked to what extent phonemic accuracy changes across trials and whether the change is predicted by AOS diagnosis and sound production severity.

methodOne hundred thirty-three participants were assigned to four diagnostic groups based on quantitative metrics (aphasia plus AOS, aphasia-only, and aphasia with two borderline speech profiles). Each participant produced four multisyllabic words 5 times consecutively. These productions were audio-recorded and transcribed phonetically and then summarized as the proportion of target phonemes that was produced accurately. Nonparametric statistics were used to analyze percent change in accuracy from the first to the last production based on diagnostic group and a broad measure of speech sound accuracy.

resultsAccuracy on the repeated words deteriorated across trials for all groups, showing reduced accuracy from the first to the last repetition for 62% of participants. Although diagnostic groups differed on the broad measure of speech sound accuracy, severity classification based on this measure did not determine degree of deterioration on the repeated words task. DISCUSSION: Responding to a request to say multisyllabic words 5 times sequentially is challenging for people with aphasia with and without AOS, and as such, performance is prone to errors even with mild impairment. For most, the task does not encourage self-correction. Instead, it promotes errors, regardless of diagnosis, and is, therefore, useful for screening purposes.

Indexed as

AphasiaApraxiasHumansSpeechSpeech DisordersSpeech Production Measurement

Identifiers

PMID36917782
PMCPMC10187966
OpenAlexW4324131754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.