Evidence map›Paper›PMID 36917398›Full record

ReviewHeart failure reviews2023

The genetic basis for adult-onset idiopathic dilated cardiomyopathy in people of African descent.

Nqoba Tsabedze, Michele Ramsay, Amanda Krause, Quinn Wells, Dineo Mpanya, Pravin Manga

Open access · hybridFull text readReview
In one paragraph

Review in Heart failure reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Discovery ofDiagnostics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nqoba TsabedzeDivision of Cardiology, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, 17 Jubilee Road, Parktown, Johannesburg, Gauteng, 2193, South Africa. Nqoba.Tsabedze@wits.ac.za.ORCID 0000-0002-7210-1447
Michele RamsaySydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-4156-4801
Amanda KrauseDivision of Human Genetics, National Health Laboratory Services and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2001, South Africa.ORCID 0000-0002-7157-0807
Quinn WellsDivision of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, 37232, TN, USA.ORCID 0000-0003-3899-0313
Dineo MpanyaDivision of Cardiology, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, 17 Jubilee Road, Parktown, Johannesburg, Gauteng, 2193, South Africa.ORCID 0000-0003-3769-4686
Pravin MangaDivision of Cardiology, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, 17 Jubilee Road, Parktown, Johannesburg, Gauteng, 2193, South Africa.ORCID 0000-0002-2709-2158
University of the Witwatersrand · ZANational Health Laboratory Service · ZAVanderbilt University Medical Center · US

Funding

Carnegie Corporation of New York B8749.RO1
6 · The paper itself

Abstract

Cardiomyopathies are a heterogeneous group of cardiac muscle disorders that result in dilated, hypertrophic, or restrictive pathophysiological entities. Dilated cardiomyopathy (DCM) is the most common form in sub-Saharan Africa (SSA). However, population-specific research studies reporting the actual burden of DCM in this region are still lacking. Also, little is known about the genetic basis of DCM in this population, and genetic testing is still not readily accessible. This review describes the common pathogenic genes implicated in DCM globally and discusses the evidence-based management of patients with DCM. We also present a summary of studies describing genes implicated or associated with DCM in patients residing in SSA.

Indexed as

Cardiomyopathy, DilatedAdultGenetic TestingHumansFamilial dilated cardiomyopathyGeneticsHeart failureIdiopathic dilated cardiomyopathyMonogenicSub-Saharan Africa

Identifiers

PMID36917398
PMCPMC10011790
OpenAlexW4324130167

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read30
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.