Evidence map›Paper›PMID 36917360›Full record

ArticleActa neurochirurgica2023

Cavitation with low-energy sonication during focused ultrasound thalamotomy for a patient with tremor-dominant Parkinson's disease: a potential risk.

Toshio Yamaguchi, Masayuki Nakano, Jinichi Sasanuma, Masahito Takasaki, Futaba Maki, Sakae Hino, Mayumi Kaburagi, Ken Iijima, Hirokazu Iwamuro, Kazuo Watanabe

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In one paragraph

Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Toshio YamaguchiInternational Academia for Focused Ultrasound Therapy, Katahira, Asaoku, Kawasaki, Kanagawa, 215-0023, Japan. yamaguchisurf@gmail.com.ORCID http://orcid.org/0000-0002-0242-7345
Masayuki NakanoDepartment of Neurosurgery, Shin-Yurigaoka General Hospital, Kawasaki, Kanagawa, Japan.
Jinichi SasanumaDepartment of Neurosurgery, Shin-Yurigaoka General Hospital, Kawasaki, Kanagawa, Japan.
Masahito TakasakiDepartment of Anesthesiology, Shin-Yurigaoka General Hospital, Kawasaki, Kanagawa, Japan.
Futaba MakiDepartment of Neurology, Shin-Yurigaoka General Hospital, Kawasaki, Kanagawa, Japan.
Sakae HinoDepartment of Neurology, Shin-Yurigaoka General Hospital, Kawasaki, Kanagawa, Japan.
Mayumi KaburagiDepartment of Neurology, Shin-Yurigaoka General Hospital, Kawasaki, Kanagawa, Japan.
Ken IijimaInternational Academia for Focused Ultrasound Therapy, Katahira, Asaoku, Kawasaki, Kanagawa, 215-0023, Japan.
Hirokazu IwamuroDepartment of Neurosurgery, Juntendo University, Bunkyo City, Tokyo, Japan.
Kazuo WatanabeSouthern Tohoku Research Institute for Neuroscience, Koriyama, Fukushima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a patient with tremor-dominant Parkinson's disease who had a mild cavitation bioeffect during magnetic resonance-guided focused ultrasound thalamotomy. During the aligning phase with low-energy sonication, cavitation caused mild dysarthria and paresthesia, prompting treatment cessation. At the same time, tremor and rigidity improved. MRI revealed extensive high-intensity lesions in the thalamus 1 day after the procedure followed by steroid infusion, which resulted in resolution of adverse events. Tremor and rigidity improved 1.5 years after the procedure. Although cavitation can relieve tremors and rigidity, it should be carefully monitored due to potential permanent adverse events by unpredictable and unknown behaviors.

Indexed as

Essential TremorParkinson DiseaseHumansMagnetic Resonance ImagingSonicationThalamusTreatment OutcomeTremorCavitationFocused ultrasound thalamotomyMagnetic resonance–guided focused ultrasoundMechanical bioeffectResting tremorTremor-dominant Parkinson’s disease

Identifiers

PMID36917360

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.