Evidence map›Paper›PMID 36917318›Full record

ArticleWiener medizinische Wochenschrift (1946)2024

Olfactory identification, cognition, depressive symptoms, and 5-year mortality in patients with subjective cognitive decline, mild cognitive impairment, and Alzheimer's disease.

Gisela Pusswald, Blaz Dapić, Carina Bum, Eva Schernhammer, Elisabeth Stögmann, Johann Lehrner

Abstract read
In one paragraph

Article in Wiener medizinische Wochenschrift (1946), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Partial Middle Turbinate Resection Versus Preservation on Olfactory Function: A Systematic Review and Meta-Analysis.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Pooled it
  3. Article
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  5. Assessment and behavioural management options for older adults with declined smell and taste functions: a scoping review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gisela PusswaldDepartment of Neurology, Medical University of Vienna, Vienna, Austria.
Blaz DapićDepartment of Neurology, Medical University of Vienna, Vienna, Austria.
Carina BumDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Eva SchernhammerDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Elisabeth StögmannDepartment of Neurology, Medical University of Vienna, Vienna, Austria.
Johann LehrnerDepartment of Neurology, Medical University of Vienna, Vienna, Austria. Johann.Lehrner@meduniwien.ac.at.ORCID http://orcid.org/0000-0001-8270-9272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAn association between odor and cognitive impairment has been shown in many studies. The objective of the present hospital-based, single-center retrospective study was to assess the impact of odor impairment on the mortality of patients with Alzheimer's disease (AD), subjective cognitive decline (SCD), and mild cognitive impairment (MCI).

methodsOdor function was measured by Sniffin Sticks (Burghart Messtechnik, Holm, Germany) and the assessment of self-reported olfactory functioning and olfaction-related quality of life (ASOF) test. Cognitive performance was assessed by an extensive neuropsychological test battery, symptoms of depression were diagnosed with the Geriatric Depressive Scale (GDS). The influence of demographic factors such as gender, age, and education were examined.

resultsAlthough the univariate analyses and pairwise post hoc comparison showed significant differences for some of the olfactory performance tests/subtests, the multivariate models showed no association between olfactory test performance and mortality among patients with cognitive impairment. "Attention," a domain of the Neuropsychological Test Battery Vienna (NTBV), as well as depressive symptoms, gender, and age, showed a significant influence on the mortality of the patient group.

conclusionLower olfactory performance showed no impact on mortality. However, decreased cognitive function of "Attention" can be considered as an influential predictor for mortality.

Indexed as

Alzheimer DiseaseCognitive DysfunctionOlfaction DisordersAgedCognitionDepressionHumansNeuropsychological TestsQuality of LifeRetrospective StudiesSmellAgingCognitive declineDementiaMortalityOlfactory impairment

Identifiers

PMID36917318
PMCPMC10959832

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.