Evidence map›Paper›PMID 36917260›Full record

ArticleEuropean radiology2023

Artificial intelligence in BreastScreen Norway: a retrospective analysis of a cancer-enriched sample including 1254 breast cancer cases.

Henrik Wethe Koch, Marthe Larsen, Hauke Bartsch, Kathinka Dæhli Kurz, Solveig Hofvind

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Henrik Wethe KochDepartment of Radiology, Stavanger University Hospital, Stavanger, Norway.
Marthe LarsenSection for Breast Cancer Screening, Cancer Registry of Norway, Oslo, Norway.
Hauke BartschDepartment of Radiology, Haukeland University Hospital, Bergen, Norway.
Kathinka Dæhli KurzDepartment of Radiology, Stavanger University Hospital, Stavanger, Norway.
Solveig HofvindSection for Breast Cancer Screening, Cancer Registry of Norway, Oslo, Norway. sshh@kreftregisteret.no.ORCID http://orcid.org/0000-0003-0178-8939
Stavanger University Hospital · NOCancer Registry of Norway · NOHaukeland University Hospital · NOUniversity of Inland Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare results of selected performance measures in mammographic screening for an artificial intelligence (AI) system versus independent double reading by radiologists.

methodsIn this retrospective study, we analyzed data from 949 screen-detected breast cancers, 305 interval cancers, and 13,646 negative examinations performed in BreastScreen Norway during the period from 2010 to 2018. An AI system scored the examinations from 1 to 10, based on the risk of malignancy. Results from the AI system were compared to screening results after independent double reading. AI score 10 was set as the threshold. The results were stratified by mammographic density.

resultsA total of 92.7% of the screen-detected and 40.0% of the interval cancers had an AI score of 10. Among women with a negative screening outcome, 9.1% had an AI score of 10. For women with the highest breast density, the AI system scored 100% of the screen-detected cancers and 48.6% of the interval cancers with an AI score of 10, which resulted in a sensitivity of 80.9% for women with the highest breast density for the AI system, compared to 62.8% for independent double reading. For women with screen-detected cancers who had prior mammograms available, 41.9% had an AI score of 10 at the prior screening round.

conclusionsThe high proportion of cancers with an AI score of 10 indicates a promising performance of the AI system, particularly for women with dense breasts. Results on prior mammograms with AI score 10 illustrate the potential for earlier detection of breast cancers by using AI in screen-reading. KEY POINTS: • The AI system scored 93% of the screen-detected cancers and 40% of the interval cancers with AI score 10. • The AI system scored all screen-detected cancers and almost 50% of interval cancers among women with the highest breast density with AI score 10. • About 40% of the screen-detected cancers had an AI score of 10 on the prior mammograms, indicating a potential for earlier detection by using AI in screen-reading.

Indexed as

Breast NeoplasmsArtificial IntelligenceBreast DensityEarly Detection of CancerFemaleHumansMammographyMass ScreeningRetrospective StudiesArtificial intelligenceBreast neoplasmMammographic densityMammographyMass screening

Identifiers

PMID36917260
PMCPMC10121532
OpenAlexW4324129861

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.