Evidence map›Paper›PMID 36917212›Full record

ReviewJournal of cell science2023

Non-muscle myosin 2 at a glance.

Melissa A Quintanilla, John A Hammer, Jordan R Beach

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of cell science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  4. Opposing Activity at the Apical Surface: An Antagonistic Collaboration Between Crumbs and Myosin II Determines Organ Shape.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
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  9. Review
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  15. Review
  16. Nonmuscle myosin 2 turnover in cells is synergistically controlled by the tail and the motor domain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Melissa A QuintanillaDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60525, USA.
John A HammerNational Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Jordan R BeachDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60525, USA.ORCID 0000-0003-0633-4928
Loyola University Chicago · USNational Institutes of Health · US

Funding

MECHANISMS OF CONTRACTILE NETWORK ASSEMBLYR35GM138183 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI Jordan Beach · 2020 to 2026
$2.8M
Investigation of Myosin 2 Regulation by RLC Kinases During Dynamic Cellular ProcessesK22HL133150 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI BEACH, JORDAN · 2017 to 2019
$737k
NHLBI NIH HHS K22 HL133150NIGMS NIH HHS R35 GM138183NIH HHS R35GM138183
6 · The paper itself

Abstract

Non-muscle myosin 2 (NM2) motors are the major contractile machines in most cell types. Unsurprisingly, these ubiquitously expressed actin-based motors power a plethora of subcellular, cellular and multicellular processes. In this Cell Science at a Glance article and the accompanying poster, we review the biochemical properties and mechanisms of regulation of this myosin. We highlight the central role of NM2 in multiple fundamental cellular processes, which include cell migration, cytokinesis, epithelial barrier function and tissue morphogenesis. In addition, we highlight recent studies using advanced imaging technologies that have revealed aspects of NM2 assembly hitherto inaccessible. This article will hopefully appeal to both cytoskeletal enthusiasts and investigators from outside the cytoskeleton field who have interests in one of the many basic cellular processes requiring actomyosin force production.

Indexed as

Actin CytoskeletonActinsActomyosinCell MovementMyosinsActinsActomyosinMyosinsActinContractilityMyosin

Identifiers

PMID36917212
PMCPMC10411949
OpenAlexW4324128757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.