Evidence map›Paper›PMID 36916882›Full record

ArticleeLife2023

A lncRNA identifies

Huaming Xu, Zhijian Li, Chao-Chung Kuo, Katrin Götz, Thomas Look, Marcelo A S de Toledo, Kristin Seré, Ivan G Costa, Martin Zenke

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Regulation of an lncRNAProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. A lncRNA identifieseLife · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Huaming XuDepartment of Cell Biology, Institute of Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
Zhijian LiInstitute for Computational Genomics, RWTH Aachen University Medical School, Aachen, Germany.
Chao-Chung KuoInstitute for Computational Genomics, RWTH Aachen University Medical School, Aachen, Germany.
Katrin GötzDepartment of Cell Biology, Institute of Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
Thomas LookDepartment of Cell Biology, Institute of Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
Marcelo A S de ToledoDepartment of Cell Biology, Institute of Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
Kristin SeréDepartment of Cell Biology, Institute of Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.
Ivan G CostaInstitute for Computational Genomics, RWTH Aachen University Medical School, Aachen, Germany.ORCID 0000-0003-2890-8697
Martin ZenkeDepartment of Cell Biology, Institute of Biomedical Engineering, RWTH Aachen University Medical School, Aachen, Germany.ORCID 0000-0002-1107-3251
Institute for Biomedical Engineering · CHGenomics (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription factors play a determining role in lineage commitment and cell differentiation. Interferon regulatory factor 8 (IRF8) is a lineage determining transcription factor in hematopoiesis and master regulator of dendritic cells (DC), an important immune cell for immunity and tolerance. IRF8 is prominently upregulated in DC development by autoactivation and controls both DC differentiation and function. However, it is unclear how

Indexed as

RNA, Long NoncodingAnimalsCell DifferentiationDendritic CellsEnhancer Elements, GeneticFeedbackInterferon Regulatory Factor-8Interferon Regulatory FactorsMiceInterferon Regulatory Factor-8Interferon Regulatory FactorsRNA, Long NoncodingCRISPRdendritic cellenhancerfeedback loopimmunologyinflammationinterferon regulatory factor 8lncRNAmouse

Identifiers

PMID36916882
PMCPMC10042546
OpenAlexW4324129565

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read90
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.