ArticleCancer medicine2023
MRI features of pediatric atypical teratoid rhabdoid tumors and medulloblastomas of the posterior fossa.
Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 14 citations in OpenAlex.
- A case-control study of MRI features in pediatric atypical teratoid rhabdoid tumor and medulloblastoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- MRI Differentiation of Anaplastic Ependymoma and Medulloblastoma with Fourth Ventricular Outlet Extension in Children.Neuroradiology · 2026Article
- Atypical Teratoid/Rhabdoid Tumor of the Lateral Ventricle: A Case Series and Experience with Molecular Subtyping-Guided Immunotherapy.Neurology international · 2026Article
- Improving final diagnosis in paediatric posterior fossa tumours: Correlation and discrepancy between radiologic diagnosis, intraoperative surgeon's diagnosis, and histopathology.Pakistan journal of medical sciences · 2025Article
- Paediatric cranial ultrasound: abnormalities of the brain in term neonates and young infants.Insights into imaging · 2025Article
- Ciprofol reduces postoperative glioma recurrence by promoting MAPK11-PML phosphorylation: insights from transcriptomic and proteomic analysis.Journal of neuro-oncology · 2025Article
- MRI findings for the pretreatment diagnosis of small Meckel's cave tumors: comparison of meningiomas and schwannomas.BMC medical imaging · 2025Article
- Advanced imaging techniques and non-invasive biomarkers in pediatric brain tumors: state of the art.Neuroradiology · 2024Review
- MRI features of pediatric atypical teratoid rhabdoid tumors and medulloblastomas of the posterior fossa.Cancer medicine · 2023Article
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8 authors at 1 institution in 1 country.
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Abstract
backgroundAtypical teratoid rhabdoid tumor (AT/RT) occurs at a younger age and is associated with a worse prognosis than medulloblastoma; however, these two tumor entities are mostly indistinguishable on neuroimaging. The aim of our study was to differentiate AT/RT and medulloblastoma based on their clinical and MRI features to enhance treatment planning and outcome prediction.
methodsFrom 2005-2021, we retrospectively enrolled 16 patients with histopathologically diagnosed AT/RT and 57 patients with medulloblastoma at our institute. We evaluated their clinical data and MRI findings, including lesion signals, intratumoral morphologies, and peritumoral/distal involvement.
resultsThe age of children with AT/RT was younger than that of children with medulloblastoma (2.8 ± 4.9 [0-17] vs. 6.5 ± 4.0 [0-18], p < 0.001), and the overall survival rate was lower (21.4% vs. 66.0%, p = 0.005). Regarding lesion signals on MRI, AT/RT had a lower ADC
conclusionsMRI findings of a lower ADC value, more peritumoral invasion, and absence of the "tumor central vein sign" may be helpful to differentiate AT/RT from medulloblastoma. These distinct MRI findings together with the younger age of AT/RT patients may explain the worse outcomes in AT/RT patients.
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