Evidence map›Paper›PMID 36916143›Full record

ArticleJournal of mass spectrometry : JMS2023

Localization of cyclopropyl groups and alkenes within glycerophospholipids using gas-phase ion/ion chemistry.

De'Shovon M Shenault, Scott A McLuckey, Elissia T Franklin

Abstract read
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In one paragraph

Article in Journal of mass spectrometry : JMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

De'Shovon M ShenaultDepartment of Chemistry, Purdue University, West Lafayette, Indiana, USA.ORCID https://orcid.org/0000-0002-9208-0655
Scott A McLuckeyDepartment of Chemistry, Purdue University, West Lafayette, Indiana, USA.ORCID https://orcid.org/0000-0002-1648-5570
Elissia T FranklinDepartment of Chemistry, Purdue University, West Lafayette, Indiana, USA.ORCID https://orcid.org/0000-0002-1017-9927

Funding

Gas-phase Bio-conjugation in the Tandem Mass Spectrometry of Peptides, Proteins,R37GM045372 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2014 to 2023
$3.1M
Mass spectrometry method with C=C location specificity for qualitative and quantitative lipid analysisR01GM118484 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM118484NIGMS NIH HHS R37 GM045372U.S. National Institute of Health (NIH) GM R01-118484U.S. National Institute of Health (NIH) GMR37-45372
6 · The paper itself

Abstract

Shotgun lipid analysis using electrospray ionization tandem mass spectrometry (ESI-MS/MS) is a common approach for the identification and characterization of glycerophohspholipids GPs. ESI-MS/MS, with the aid of collision-induced dissociation (CID), enables the characterization of GP species at the headgroup and fatty acyl sum compositional levels. However, important structural features that are often present, such as carbon-carbon double bond(s) and cyclopropane ring(s), can be difficult to determine. Here, we report the use of gas-phase charge inversion reactions that, in combination with CID, allow for more detailed structural elucidation of GPs. CID of a singly deprotonated GP, [GP - H]

Indexed as

cyclopropane locationdouble bond locationglycerophospholipidsion/ion reactionsshotgun lipidomics

Identifiers

PMID36916143
PMCPMC10014902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.